Causal Association Between Immune Cell Traits and Risk of Multiple Malignant and Nonmalignant CNS Diseases: A Mendelian Randomization and Single‐Cell Transcriptomic Analysis
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DOI: 10.1002/brb3.70632
Abstract: The influence of immune cell traits (ICTs) on the onset of multiple brain diseases has been previously investigated; however, it is limited by the sample size or colocalization evidence. Besides, the impact remains inconclusive. read more here.
Keywords: association immune; cell traits; cell; immune cell ... See more keywords
Update on the practice of premarital screening for sickle cell traits in Africa: a systematic review and meta-analysis
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DOI: 10.1186/s12889-024-19001-y
Abstract: Screening for sickle cell traits before marriage or producing children is one of the outstanding preventive measures for sickle cell disease (SCD).The disease is a collection of inherited blood disorders that impact millions globally, with… read more here.
Keywords: screening sickle; practice premarital; cell traits; cell ... See more keywords
Blood cell traits and risk of glaucoma: A two-sample mendelian randomization study
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DOI: 10.3389/fgene.2023.1142773
Abstract: Importance: Glaucoma is the second leading cause of blindness in the world. The causal direction and magnitude of the association between blood cell traits and glaucoma is uncertain because of the susceptibility of observational studies… read more here.
Keywords: cell; glaucoma; count; blood ... See more keywords
The causal relationship between immune cell traits and schizophrenia: a Mendelian randomization analysis
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DOI: 10.3389/fimmu.2024.1452214
Abstract: Introduction The complex and unresolved pathogenesis of schizophrenia has posed significant challenges to its diagnosis and treatment. While recent research has established a clear association between immune function and schizophrenia, the causal relationship between the… read more here.
Keywords: schizophrenia; cell traits; cell; causal relationship ... See more keywords
Genetically Predicted Immune Cell Traits Mediate the Causal Association Between Plasma Metabolites and Colorectal Cancer
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DOI: 10.7150/jca.101011
Abstract: Background: Relevant studies have demonstrated that plasma metabolites and immune cell characteristics are closely related to colorectal cancer (CRC). However, the causal relationship among these factors remains unclear, particularly regarding whether immune cell traits mediate… read more here.
Keywords: cell; immune cell; plasma metabolites; cell traits ... See more keywords