Revealing the Transcriptional and Metabolic Characteristics of Sebocytes Based on the Donkey Cell Transcriptome Atlas
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202413819
Abstract: Worldwide, donkeys (Equus asinus) are valued for their meat and milk, and in China also for the medical value of their skin. Physiological characteristics are key to the donkey's adaptability, including their digestive, respiratory, and… read more here.
Keywords: cell; revealing transcriptional; donkey skin; transcriptional metabolic ... See more keywords
Single‐cell transcriptome analysis of fractional CO2 laser efficiency in treating a mouse model of alopecia
Sign Up to like & getrecommendations! Published in 2022 at "Lasers in Surgery and Medicine"
DOI: 10.1002/lsm.23590
Abstract: Hair loss, including alopecia, is a common dermatological issue worldwide. At present, the application of fractional carbon dioxide (CO2) laser in the treatment of alopecia has been documented; however, the results vary between reports. These… read more here.
Keywords: co2 laser; transcriptome analysis; cell transcriptome; laser ... See more keywords
Single-Cell Transcriptome Profiling.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1103-6_16
Abstract: Over the last decade, single cell RNA sequencing (scRNAseq) became an increasingly viable solution for analyzing cellular heterogeneity and cell-specific expression differences. While not as mature or fully realized as bulk sequencing, newly developed computational… read more here.
Keywords: single cell; cell transcriptome; biology; transcriptome profiling ... See more keywords
Single-Cell Transcriptome Profiling of Protozoan and Metazoan Parasites.
Sign Up to like & getrecommendations! Published in 2018 at "Trends in parasitology"
DOI: 10.1016/j.pt.2018.04.009
Abstract: Single-cell RNA sequencing (scRNAseq) technologies are changing the way we study populations of cells by allowing for an unbiased characterization of the composition of these populations. This Forum article highlights outstanding questions in parasitology that… read more here.
Keywords: single cell; parasitology; cell transcriptome; profiling protozoan ... See more keywords
Single-cell transcriptome atlas of testes from mice with high-fat diets
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Data"
DOI: 10.1038/s41597-024-03435-5
Abstract: Obesity is accompanied by multiple known health risks and increased morbidity, and obese men display reduced reproductive health. However, the impact of obesity on the testes at the molecular levels remain inadequately explored. This is… read more here.
Keywords: cell transcriptome; single cell; obesity; cell ... See more keywords
Single-cell transcriptome analysis profiling lymphatic invasion-related TME in colorectal cancer
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-59656-6
Abstract: Lymphatic invasion (LI) is extremely aggressive and induces worse prognosis among patients with colorectal cancer (CRC). Thus, it is critical to characterize the cellular and molecular mechanisms underlying LI in order to establish novel and… read more here.
Keywords: colorectal cancer; lymphatic invasion; cell transcriptome; single cell ... See more keywords
Single-cell transcriptome analysis reveals secretin as a hallmark of human enteroendocrine cell maturation
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-63699-0
Abstract: The traditional nomenclature of enteroendocrine cells (EECs), established in 1977, applied the “one cell - one hormone” dogma, which distinguishes subpopulations based on the secretion of a specific hormone. These hormone-specific subpopulations included S cells… read more here.
Keywords: single cell; cell; expression; eecs ... See more keywords
Robust classification of single-cell transcriptome data by nonnegative matrix factorization
Sign Up to like & getrecommendations! Published in 2017 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btw607
Abstract: Motivation: Single-cell transcriptome data provide unprecedented resolution to study heterogeneity in cell populations and present a challenge for unsupervised classification. Popular methods, like principal component analysis (PCA), often suffer from the high level of noise… read more here.
Keywords: single cell; classification; cell transcriptome; transcriptome data ... See more keywords
ETMR-17. SINGLE-CELL TRANSCRIPTOME ANALYSIS OF ETMR PATIENT SAMPLES
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaa222.220
Abstract: Abstract Brain tumors are comprised of cells with heterogeneous genetic and transcriptional states, resulting in substantial phenotypic diversity. This diversity is particularly evident in embryonal tumor with multilayered rosettes (ETMR), which shows a striking bi-phasic… read more here.
Keywords: single cell; etmr; cell transcriptome; malignant cell ... See more keywords
Single-cell transcriptome analysis elucidates the microenvironmental interactions between colorectal cancer and sarcopenia
Sign Up to like & getrecommendations! Published in 2025 at "Medicine"
DOI: 10.1097/md.0000000000046084
Abstract: Colorectal cancer (CRC) often occurs in combination with sarcopenia (SP), which affects the prognosis of CRC, but the histopathological mechanisms underlying this process are unclear. Single-cell transcriptome technology provides a tool for resolving multi-organ pathological… read more here.
Keywords: colorectal cancer; single cell; crc; cell ... See more keywords
Single-cell transcriptome profiles of Drosophila fruitless-expressing neurons from both sexes
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.1101/2022.03.09.483618
Abstract: Drosophila melanogaster reproductive behaviors are orchestrated by fruitless neurons. We performed single-cell RNA-sequencing on fru P1 pupal neurons. Uniform Manifold Approximation and Projection (UMAP) clustering generates an atlas containing 113 clusters. While the male and… read more here.
Keywords: cell; cell transcriptome; expression; transcriptome profiles ... See more keywords