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   Articles with "cell transcriptome" as a keyword



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Single‐cell transcriptome analysis of fractional CO2 laser efficiency in treating a mouse model of alopecia

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recommendations! Published in 2022 at "Lasers in Surgery and Medicine"

DOI: 10.1002/lsm.23590

Abstract: Hair loss, including alopecia, is a common dermatological issue worldwide. At present, the application of fractional carbon dioxide (CO2) laser in the treatment of alopecia has been documented; however, the results vary between reports. These… read more here.

Keywords: co2 laser; transcriptome analysis; cell transcriptome; laser ... See more keywords
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Single-Cell Transcriptome Profiling.

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recommendations! Published in 2021 at "Methods in molecular biology"

DOI: 10.1007/978-1-0716-1103-6_16

Abstract: Over the last decade, single cell RNA sequencing (scRNAseq) became an increasingly viable solution for analyzing cellular heterogeneity and cell-specific expression differences. While not as mature or fully realized as bulk sequencing, newly developed computational… read more here.

Keywords: single cell; cell transcriptome; biology; transcriptome profiling ... See more keywords
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Single-Cell Transcriptome Profiling of Protozoan and Metazoan Parasites.

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recommendations! Published in 2018 at "Trends in parasitology"

DOI: 10.1016/j.pt.2018.04.009

Abstract: Single-cell RNA sequencing (scRNAseq) technologies are changing the way we study populations of cells by allowing for an unbiased characterization of the composition of these populations. This Forum article highlights outstanding questions in parasitology that… read more here.

Keywords: single cell; parasitology; cell transcriptome; profiling protozoan ... See more keywords
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Robust classification of single-cell transcriptome data by nonnegative matrix factorization

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recommendations! Published in 2017 at "Bioinformatics"

DOI: 10.1093/bioinformatics/btw607

Abstract: Motivation: Single-cell transcriptome data provide unprecedented resolution to study heterogeneity in cell populations and present a challenge for unsupervised classification. Popular methods, like principal component analysis (PCA), often suffer from the high level of noise… read more here.

Keywords: single cell; classification; cell transcriptome; transcriptome data ... See more keywords
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ETMR-17. SINGLE-CELL TRANSCRIPTOME ANALYSIS OF ETMR PATIENT SAMPLES

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recommendations! Published in 2020 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noaa222.220

Abstract: Abstract Brain tumors are comprised of cells with heterogeneous genetic and transcriptional states, resulting in substantial phenotypic diversity. This diversity is particularly evident in embryonal tumor with multilayered rosettes (ETMR), which shows a striking bi-phasic… read more here.

Keywords: single cell; etmr; cell transcriptome; malignant cell ... See more keywords
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Single-cell transcriptome profiles of Drosophila fruitless-expressing neurons from both sexes

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recommendations! Published in 2022 at "eLife"

DOI: 10.1101/2022.03.09.483618

Abstract: Drosophila melanogaster reproductive behaviors are orchestrated by fruitless neurons. We performed single-cell RNA-sequencing on fru P1 pupal neurons. Uniform Manifold Approximation and Projection (UMAP) clustering generates an atlas containing 113 clusters. While the male and… read more here.

Keywords: cell; cell transcriptome; expression; transcriptome profiles ... See more keywords
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Single-cell transcriptome analysis reveals cell lineage specification in temporal-spatial patterns in human cortical development.

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recommendations! Published in 2020 at "Science advances"

DOI: 10.1126/sciadv.aaz2978

Abstract: Neurogenesis processes differ in different areas of the cortex in many species, including humans. Here, we performed single-cell transcriptome profiling of the four cortical lobes and pons during human embryonic and fetal development. We identified… read more here.

Keywords: single cell; cortical development; cell transcriptome; temporal spatial ... See more keywords
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Abstract 5652: IL-19 blockade reprograms glioblastoma immunosuppressive microenvironment and overcomes chemo-resistance as revealed by single-cell transcriptome analyses

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recommendations! Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-5652

Abstract: Glioblastoma multiforme (GBM) is the most aggressive brain tumor with chemo-resistant, immunosuppressive, and invasive property. Despite the application of standard therapies which include a combination of surgery, radiotherapy, and temozolomide (TMZ) chemotherapy, tumor inevitably recurred… read more here.

Keywords: cell; cell transcriptome; immunosuppressive microenvironment; blockade ... See more keywords
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Single cell transcriptome analysis reveals disease-defining T cell subsets in the tumor microenvironment of classic Hodgkin lymphoma.

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recommendations! Published in 2019 at "Cancer discovery"

DOI: 10.1158/2159-8290.cd-19-0680

Abstract: Hodgkin lymphoma (HL) is characterized by an extensively dominant tumor microenvironment (TME) composed of different types of non-cancerous immune cells with rare malignant cells. Characterization of the cellular components and their spatial relationship is crucial… read more here.

Keywords: tumor microenvironment; cell transcriptome; hodgkin lymphoma; cell ... See more keywords
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Single-cell transcriptome analyses reveal microglia types associated with proliferative retinopathy

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recommendations! Published in 2022 at "JCI Insight"

DOI: 10.1172/jci.insight.160940

Abstract: Pathological angiogenesis is a major cause of irreversible blindness in individuals of all age groups with proliferative retinopathy (PR). Mononuclear phagocytes (MPs) within neovascular areas contribute to aberrant retinal angiogenesis. Due to their cellular heterogeneity,… read more here.

Keywords: cell transcriptome; proliferative retinopathy; single cell; angiogenesis ... See more keywords
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EBV miRNAs are potent effectors of tumor cell transcriptome remodeling in promoting immune escape

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recommendations! Published in 2021 at "PLoS Pathogens"

DOI: 10.1371/journal.ppat.1009217

Abstract: The Epstein Barr virus (EBV) contributes to the tumor phenotype through a limited set of primarily non-coding viral RNAs, including 31 mature miRNAs. Here we investigated the impact of EBV miRNAs on remodeling the tumor… read more here.

Keywords: cell transcriptome; tumor cell; mirnas potent; ebv mirnas ... See more keywords