Nanovaccine‐Mediated Cell Selective Delivery of Neoantigens Potentiating Adoptive Dendritic Cell Transfer for Personalized Immunization
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202104068
Abstract: Neoantigen vaccines and adoptive dendritic cell (DC) transfer are major clinical approaches to initiate personalized immunity in cancer patients. However, the immunization efficacy is largely limited by the in vivo trajectory including neoantigens’ access to… read more here.
Keywords: personalized immunization; delivery; cell; transfer ... See more keywords
Mechanisms of HIV‐1 cell‐to‐cell transfer to myeloid cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.4mr0322-737r
Abstract: In addition to CD4+ T lymphocytes, cells of the myeloid lineage such as macrophages, dendritic cells (DCs), and osteoclasts (OCs) are emerging as important target cells for HIV‐1, as they likely participate in all steps… read more here.
Keywords: cell; cell cell; myeloid cells; cell transfer ... See more keywords
Immune biomarkers for predicting response to adoptive cell transfer as cancer treatment
Sign Up to like & getrecommendations! Published in 2018 at "Immunogenetics"
DOI: 10.1007/s00251-018-1083-1
Abstract: Adoptive cell transfer (ACT) is a form of personalised immunotherapy which has shown promising results in metastasised cancer. For this treatment, autologous T lymphocytes are selected and stimulated in vitro before re-administration in large numbers.… read more here.
Keywords: response; adoptive cell; treatment; cell transfer ... See more keywords
Manipulating the tumor microenvironment by adoptive cell transfer of CAR T-cells
Sign Up to like & getrecommendations! Published in 2018 at "Mammalian Genome"
DOI: 10.1007/s00335-018-9756-5
Abstract: T-cells expressing synthetic chimeric antigen receptors (CARs) have revolutionized immuno-oncology and highlighted the use of adoptive cell transfer, for the treatment of cancer. The phenomenal clinical success obtained in the treatment of hematological malignancies with… read more here.
Keywords: adoptive cell; cell transfer; car cells; car ... See more keywords
A new model to study cell-to-cell transfer of αSynuclein in vivo.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.07.053
Abstract: Parkinson's disease (PD) compromises motor control due to the loss of dopaminergic neurons in the substantia nigra pars compacta. At the histopathological level, PD is characterized by the accumulation of Lewy bodies, large protein inclusions… read more here.
Keywords: protein; cell; syn; cell transfer ... See more keywords
T cell transfer after allo-HSCT in AML
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Clinical Oncology"
DOI: 10.1038/s41571-019-0251-z
Abstract: Patients with acute myeloid leukaemia (AML) receiving allogeneic haematopoietic stem-cell transplantation (allo-HSCT) have a high risk of relapse. The results of a phase I study now published reveal that the infusion of T cells selected… read more here.
Keywords: allo hsct; infusion; relapse; cell transfer ... See more keywords
P032 MiR-511 deficiency aggravates T cell transfer colitis in mice
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjab076.161
Abstract: MiR-511 is embedded in intron region 5 of the CD206/MRC1 gene, expressed by macrophage and dendritic cell populations. In this study, we aimed to investigate the effect of MiR-511 deficiency on intestinal inflammation in a… read more here.
Keywords: colitis; mice; transfer colitis; cell transfer ... See more keywords
IMMU-25. MAGNETIC PARTICLE IMAGING FOR NON-INVASIVE TRACKING OF ADOPTIVE CELL TRANSFER IN CANCER IMMUNOTHERAPY
Sign Up to like & getrecommendations! Published in 2019 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noz175.518
Abstract: Adoptive cell therapies (ACT) are strategies being explored to boost the immune response against cancer. ACT cancer immunotherapies are effective against metastatic melanoma, leukemia, and lymphoma, but face challenges in treating other solid tumors, such… read more here.
Keywords: magnetic particle; adoptive cell; cell transfer; cancer ... See more keywords
Adoptive cell transfer therapy for melanoma
Sign Up to like & getrecommendations! Published in 2022 at "Experimental Dermatology"
DOI: 10.1111/exd.14707
Abstract: Adoptive cell transfer (ACT) of tumor‐infiltrating lymphocytes (TILs) for melanoma is an example of the most successful cancer immune therapy. It achieves a durable complete response about ~20% of patients, and they might be cured.… read more here.
Keywords: adoptive cell; cell transfer; therapy; til therapy ... See more keywords
Clinically relevant orthotopic pancreatic cancer models for adoptive T cell transfer therapy
Sign Up to like & getrecommendations! Published in 2024 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2023-008086
Abstract: Background Pancreatic ductal adenocarcinoma (PDAC) is an aggressive tumor. Prognosis is poor and survival is low in patients diagnosed with this disease, with a survival rate of ~12% at 5 years. Immunotherapy, including adoptive T… read more here.
Keywords: therapy; cell; cell transfer; transfer therapy ... See more keywords
Adoptive cell transfer therapy with ex vivo primed peripheral lymphocytes in combination with chemotherapy in locally advanced or metastatic triple-negative breast cancer: the ImmunoBreast phase Ib clinical trial
Sign Up to like & getrecommendations! Published in 2025 at "Journal for ImmunoTherapy of Cancer"
DOI: 10.1136/jitc-2025-012213
Abstract: Background Adoptive cell transfer-based immunotherapy holds promise for treating advanced cancer. However, a key challenge remains: generating sufficient numbers of lymphocytes capable of recognizing and targeting a broad range of cancer antigens. We recently developed… read more here.
Keywords: cancer; trial; carboplatin gemcitabine; locally advanced ... See more keywords