Articles with "cell transformation" as a keyword



High temperatures promote cell-to-cell plasmid transformation in Escherichia coli.

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Published in 2019 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2019.05.134

Abstract: Bacteria continuously change their genetic characteristics to adapt to the changing environment by means of horizontal gene transfer. Although three conventional mechanisms of horizontal gene transfer are well known (transformation, transduction, and conjugation), new variations… read more here.

Keywords: high temperatures; cell; transformation; cell transformation ... See more keywords

TRIM36 hypermethylation is involved in polycyclic aromatic hydrocarbons-induced cell transformation.

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Published in 2017 at "Environmental pollution"

DOI: 10.1016/j.envpol.2017.03.001

Abstract: Long term exposure to polycyclic aromatic hydrocarbons (PAHs) is associated with the increasing risk of lung cancer. To identify differentially hypermethylated genes associated with PAHs-induced carcinogenicity, we performed genome-wide DNA methylation analysis in 20 μM benzo(a)pyrene… read more here.

Keywords: hypermethylation; aromatic hydrocarbons; cell transformation; trim36 hypermethylation ... See more keywords

Epigenetic changes in the early stage of silica-induced cell transformation

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Published in 2017 at "Nanotoxicology"

DOI: 10.1080/17435390.2017.1382599

Abstract: Abstract The increasing use of nanomaterials in numerous domains has led to growing concern about their potential toxicological properties, and the potential risk to human health posed by silica nanoparticles remains under debate. Recent studies… read more here.

Keywords: expression; cell transformation; early stage;

EBNA leader protein orchestrates chromatin architecture remodeling during Epstein-Barr virus-induced B cell transformation

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Published in 2025 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkaf629

Abstract: Abstract Epstein-Barr virus Nuclear Antigen Leader Protein (EBNA-LP) plays a pivotal role in the transformation of B cells by Epstein-Barr virus (EBV), functioning independently of EBNA2 to regulate chromatin architecture and gene expression. Our study… read more here.

Keywords: chromatin architecture; cell transformation; epstein barr; transformation ... See more keywords

Transcriptional circuits in B cell transformation

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Published in 2017 at "Current Opinion in Hematology"

DOI: 10.1097/moh.0000000000000352

Abstract: Purpose of review Loss of IKAROS in committed B cell precursors causes a block in differentiation while at the same time augments aberrant cellular properties, such as bone marrow stromal adhesion, self-renewal and resistance to… read more here.

Keywords: cell differentiation; circuits cell; differentiation; cell transformation ... See more keywords

Brentuximab extravasation injury in a patient with mycosis fungoides with large cell transformation

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Published in 2022 at "Dermatologic Therapy"

DOI: 10.1111/dth.15751

Abstract: non-Hodgkin lymphomas extracutaneous the of and are indo-lent. 1,2 CD30 positivity may suggest the potential for large cell transformation and progression. 3 Brentuximab vedotin (BV) is an anti-CD30 antibody-drug conjugate newly approved to treat CD30… read more here.

Keywords: large cell; cell transformation; brentuximab extravasation;

Abstract 4015: Histone-lysine methyltransferase up-regulation plays a causal role in hexavalent chromium-induced cancer stem cell-like property and cell transformation

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Published in 2018 at "Cancer Research"

DOI: 10.1158/1538-7445.am2018-4015

Abstract: Chromium (Cr) and its compounds have been widely used in the manufacture of many consumer products. In addition to occupational exposure of millions of industrial workers, large numbers of general population are also commonly exposed… read more here.

Keywords: cancer; exposure; like property; cell transformation ... See more keywords

Comparative structural studies on Bovine papillomavirus E6 oncoproteins: Novel insights into viral infection and cell transformation from homology modeling and molecular dynamics simulations

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Published in 2024 at "Genetics and Molecular Biology"

DOI: 10.1590/1678-4685-gmb-2023-0346

Abstract: Abstract Bovine papillomavirus (BPV) infects cattle cells worldwide, leading to hyperproliferative lesions and the potential development of cancer, driven by E5, E6, and E7 oncoproteins along with other cofactors. E6 oncoprotein binds experimentally to various… read more here.

Keywords: bpv; cell transformation; transformation; bovine papillomavirus ... See more keywords

Modeling Radiation-Induced Neoplastic Cell Transformation In Vitro and Tumor Induction In Vivo with the Local Effect Model

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Published in 2021 at "Radiation Research"

DOI: 10.1667/rade-20-00160.1

Abstract: Ionizing radiation induces DNA damage to cycling cells which, if left unrepaired or misrepaired, can cause cell inactivation or heritable, viable mutations. The latter can lead to cell transformation, which is thought to be an… read more here.

Keywords: radiation; model; cell; cell transformation ... See more keywords

Autophagy in Cancer Cell Transformation: A Potential Novel Therapeutic Strategy.

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Published in 2022 at "Current cancer drug targets"

DOI: 10.2174/1568009622666220428102741

Abstract: Basal autophagy plays a crucial role in maintaining intracellular homeostasis and prevents the cell from escaping the cell cycle regulation mechanisms and being cancerous. Mitophagy and nucleophagy are essential for cell health. Autophagy plays a… read more here.

Keywords: cell; cell transformation; regulation; cancer cell ... See more keywords

MiR-150 in HTLV-1 infection and T-cell transformation

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.974088

Abstract: Human T-cell leukemia virus-1 (HTLV-1) is a retrovirus that persistently infects CD4+ T-cells, and is the causative agent of adult T-cell leukemia/lymphoma (ATLL), tropical spastic paraparesis/HTLV-1-associated myelopathy (TSP/HAM) and several inflammatory diseases. T-cell transformation by… read more here.

Keywords: cell; htlv infection; 150 htlv; cell transformation ... See more keywords