High temperatures promote cell-to-cell plasmid transformation in Escherichia coli.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.05.134
Abstract: Bacteria continuously change their genetic characteristics to adapt to the changing environment by means of horizontal gene transfer. Although three conventional mechanisms of horizontal gene transfer are well known (transformation, transduction, and conjugation), new variations… read more here.
Keywords: high temperatures; cell; transformation; cell transformation ... See more keywords
TRIM36 hypermethylation is involved in polycyclic aromatic hydrocarbons-induced cell transformation.
Sign Up to like & getrecommendations! Published in 2017 at "Environmental pollution"
DOI: 10.1016/j.envpol.2017.03.001
Abstract: Long term exposure to polycyclic aromatic hydrocarbons (PAHs) is associated with the increasing risk of lung cancer. To identify differentially hypermethylated genes associated with PAHs-induced carcinogenicity, we performed genome-wide DNA methylation analysis in 20 μM benzo(a)pyrene… read more here.
Keywords: hypermethylation; aromatic hydrocarbons; cell transformation; trim36 hypermethylation ... See more keywords
Epigenetic changes in the early stage of silica-induced cell transformation
Sign Up to like & getrecommendations! Published in 2017 at "Nanotoxicology"
DOI: 10.1080/17435390.2017.1382599
Abstract: Abstract The increasing use of nanomaterials in numerous domains has led to growing concern about their potential toxicological properties, and the potential risk to human health posed by silica nanoparticles remains under debate. Recent studies… read more here.
Keywords: expression; cell transformation; early stage;
Transcriptional circuits in B cell transformation
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Hematology"
DOI: 10.1097/moh.0000000000000352
Abstract: Purpose of review Loss of IKAROS in committed B cell precursors causes a block in differentiation while at the same time augments aberrant cellular properties, such as bone marrow stromal adhesion, self-renewal and resistance to… read more here.
Keywords: cell differentiation; circuits cell; differentiation; cell transformation ... See more keywords
Brentuximab extravasation injury in a patient with mycosis fungoides with large cell transformation
Sign Up to like & getrecommendations! Published in 2022 at "Dermatologic Therapy"
DOI: 10.1111/dth.15751
Abstract: non-Hodgkin lymphomas extracutaneous the of and are indo-lent. 1,2 CD30 positivity may suggest the potential for large cell transformation and progression. 3 Brentuximab vedotin (BV) is an anti-CD30 antibody-drug conjugate newly approved to treat CD30… read more here.
Keywords: large cell; cell transformation; brentuximab extravasation;
Abstract 4015: Histone-lysine methyltransferase up-regulation plays a causal role in hexavalent chromium-induced cancer stem cell-like property and cell transformation
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-4015
Abstract: Chromium (Cr) and its compounds have been widely used in the manufacture of many consumer products. In addition to occupational exposure of millions of industrial workers, large numbers of general population are also commonly exposed… read more here.
Keywords: cancer; exposure; like property; cell transformation ... See more keywords
Modeling Radiation-Induced Neoplastic Cell Transformation In Vitro and Tumor Induction In Vivo with the Local Effect Model
Sign Up to like & getrecommendations! Published in 2021 at "Radiation Research"
DOI: 10.1667/rade-20-00160.1
Abstract: Ionizing radiation induces DNA damage to cycling cells which, if left unrepaired or misrepaired, can cause cell inactivation or heritable, viable mutations. The latter can lead to cell transformation, which is thought to be an… read more here.
Keywords: radiation; model; cell; cell transformation ... See more keywords
Autophagy in Cancer Cell Transformation: A Potential Novel Therapeutic Strategy.
Sign Up to like & getrecommendations! Published in 2022 at "Current cancer drug targets"
DOI: 10.2174/1568009622666220428102741
Abstract: Basal autophagy plays a crucial role in maintaining intracellular homeostasis and prevents the cell from escaping the cell cycle regulation mechanisms and being cancerous. Mitophagy and nucleophagy are essential for cell health. Autophagy plays a… read more here.
Keywords: cell; cell transformation; regulation; cancer cell ... See more keywords
MiR-150 in HTLV-1 infection and T-cell transformation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.974088
Abstract: Human T-cell leukemia virus-1 (HTLV-1) is a retrovirus that persistently infects CD4+ T-cells, and is the causative agent of adult T-cell leukemia/lymphoma (ATLL), tropical spastic paraparesis/HTLV-1-associated myelopathy (TSP/HAM) and several inflammatory diseases. T-cell transformation by… read more here.
Keywords: cell; htlv infection; 150 htlv; cell transformation ... See more keywords
Regulation of Interleukin-36γ/IL-36R Signaling Axis by PIN1 in Epithelial Cell Transformation and Breast Tumorigenesis
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14153654
Abstract: Simple Summary Members of the interleukin (IL)-1 cytokine family exhibit dual functions in the regulation of inflammation and cancer. Recent studies have shown the critical role of IL-36γ, the newly identified IL-1 family member, in… read more here.
Keywords: cell transformation; breast; cancer; pin1 ... See more keywords
In Vitro Cell Transformation Assays: A Valuable Approach for Carcinogenic Potentiality Assessment of Nanomaterials
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24098219
Abstract: This review explores the application of in vitro cell transformation assays (CTAs) as a screening platform to assess the carcinogenic potential of nanomaterials (NMs) resulting from continuously growing industrial production and use. The widespread application… read more here.
Keywords: assays valuable; vitro cell; cell transformation; transformation assays ... See more keywords