Expression profiles of miRNAs in giant cell tumor of bone showed miR‐187‐5p and miR‐1323 can regulate biological functions through inhibiting FRS2
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DOI: 10.1002/cam4.2853
Abstract: Giant cell tumor of bone (GCTB) is considered to be a kind of borderline tumor, which has a tendency to recur and translocate. MicroRNAs are one type of small noncoding RNA, which can inhibit the… read more here.
Keywords: giant cell; cell tumor; tumor bone; tumor ... See more keywords
Malignant granular cell tumor: Clinical features and long‐term survival
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DOI: 10.1002/jso.25227
Abstract: Malignant granular cell tumor GCT (mGCT) has not been well described. We sought to investigate associations between tumor characteristics, treatments and survival. read more here.
Keywords: granular cell; cell tumor; tumor clinical; malignant granular ... See more keywords
Sclerostin immunohistochemical staining in surgically treated giant cell tumor of bone
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.26903
Abstract: Giant cell tumor of bone (GCTB) is a destructive lesion with a high potential for recurrence. RANK‐ligand targeted therapy has provided promising, yet mixed results. Sclerostin (SOST) inhibition results in a net anabolic response and… read more here.
Keywords: cell tumor; tumor bone; giant cell;
A prospective real‐world study of the diffuse‐type tenosynovial giant cell tumor patient journey: A 2‐year observational analysis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.27067
Abstract: Diffuse‐tenosynovial giant cell tumor (D‐TGCT) is a rare, locally aggressive, typically benign neoplasm affecting mainly large joints, representing a wide clinical spectrum. We provide a picture of the treatment journey of D‐TGCT patients as a… read more here.
Keywords: cell tumor; tenosynovial giant; year observational; giant cell ... See more keywords
Unusual manifestations of diffuse-type tenosynovial giant cell tumor in two patients: importance of radiologic-pathologic correlation
Sign Up to like & getrecommendations! Published in 2019 at "Skeletal Radiology"
DOI: 10.1007/s00256-019-03325-7
Abstract: Diffuse-type tenosynovial giant cell tumor (TSGCT) is a rare, locally aggressive neoplasm. It most commonly occurs in the knee, followed by the hip, and has distinctive imaging features, including mass-like foci of low T2 signal… read more here.
Keywords: giant cell; tenosynovial giant; importance radiologic; cell tumor ... See more keywords
Denosumab treatment for giant-cell tumor of bone: a systematic review of the literature
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Orthopaedic and Trauma Surgery"
DOI: 10.1007/s00402-019-03167-x
Abstract: BackgroundDenosumab is a human monoclonal antibody (mAb) that specifically inhibits tumor-associated bone lysis through the RANKL pathway and has been used as neoadjuvant therapy for giant-cell tumor of bone (GCTB) in surgical as well as… read more here.
Keywords: giant cell; cell tumor; treatment; denosumab treatment ... See more keywords
Giant Cell Tumor of Bone: An Update
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DOI: 10.1007/s11912-021-01047-5
Abstract: To highlight the new developments in the management of advanced giant cell tumor of bone, a rare locally aggressive benign tumor, which was traditionally managed with surgery alone by either curettage and local adjuvant therapy,… read more here.
Keywords: giant cell; cell tumor; tumor bone; tumor ... See more keywords
Clinical and Radiological Profile of Ten Interesting Though Rare Presentations of Giant Cell Tumor of Bone
Sign Up to like & getrecommendations! Published in 2020 at "Indian Journal of Surgical Oncology"
DOI: 10.1007/s13193-020-01134-2
Abstract: Giant cell tumor (GCT) is a benign but locally aggressive lesion of the bone. They are common in skeletally matured individuals with female preponderance. Unusual presentations can occur rarely. This study aims to find out… read more here.
Keywords: giant cell; clinical radiological; cell tumor; bone ... See more keywords
A Rare Intramuscular Tumor in Gracilis Muscle: Granular Cell Tumor
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DOI: 10.1007/s13193-020-01172-w
Abstract: Granular cell tumors are rare benign soft tissue tumors [1]. Granular cell tumor was first described by Russian pathologist Abrissokoff as myeloblastoma [2]. Currently, it was proven to be of neural origin due to the… read more here.
Keywords: tumor gracilis; cell tumor; gracilis muscle; granular cell ... See more keywords
Granular cell tumor coexisting with adenocarcinoma in the stomach: Report of a rare case
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DOI: 10.1016/j.amsu.2021.102271
Abstract: Introduction and importance: Granular cell tumor (GCT) is a benign, mesenchymal tumor that originates from Schwann cells. Case presentation A 75-year-old Japanese woman was referred to our hospital due to epigastric discomfort. Upper gastrointestinal endoscopy… read more here.
Keywords: rare case; cell tumor; case; stomach ... See more keywords
Malignant gastrointestinal neuroectodermal tumor: Cytologic, histologic, immunohistochemical, and molecular pitfalls.
Sign Up to like & getrecommendations! Published in 2021 at "Annals of diagnostic pathology"
DOI: 10.1016/j.anndiagpath.2021.151813
Abstract: Malignant gastrointestinal neuroectodermal tumor (GNET) is a rare malignant primary gastrointestinal mesenchymal tumor which can be diagnosed via fine-needle aspiration (FNA) cytology. In the context of FNA, the diagnosis requires a cell block and the… read more here.
Keywords: malignant gastrointestinal; cell tumor; gastrointestinal neuroectodermal; neuroectodermal tumor ... See more keywords