Combination vinblastine, prednisolone and toceranib phosphate for treatment of grade II and III mast cell tumours in dogs
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DOI: 10.1002/vms3.106
Abstract: Abstract This retrospective study evaluates the progression‐free interval and survival outcomes of 40 canine (Canis familiaris) patients with Patnaik grade II and III mast cell tumours treated with combination vinblastine, prednisolone and toceranib phosphate from… read more here.
Keywords: combination; iii mast; grade iii; mast cell ... See more keywords
Canine mast cell tumours part I: Clinical and survival outcomes
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DOI: 10.1002/vms3.812
Abstract: Abstract Background Dogs have a species‐specific susceptibility for developing mast cell tumours (MCTs). Mutations in the KIT proto‐oncogene (KIT) are known to contribute to the neoplastic biology of mast cells. In dogs, the most common… read more here.
Keywords: kit; mast; cell tumours; mutation ... See more keywords
[Intracranial germ cell tumours: A 21-year review].
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DOI: 10.1016/j.anpedi.2016.03.005
Abstract: INTRODUCTION Intracranial germ cell tumours are rare in children. They are a heterogeneous group of neoplasms that show different clinical manifestations despite having a common origin. PATIENTS AND METHODS A retrospective analysis was carried out… read more here.
Keywords: intracranial germ; cell tumours; germ cell; diagnosis ... See more keywords
A multicentre retrospective cohort study of ovarian germ cell tumours: Evidence for chemotherapy de-escalation and alignment of paediatric and adult practice
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DOI: 10.1016/j.ejca.2019.03.001
Abstract: Background Adult guidelines recommend BEP (bleomycin, etoposide, cisplatin) for all ovarian germ cell tumours, causing debilitating toxicities in young patients who will survive long term. Paediatricians successfully reduce toxicities by using lower bleomycin doses and… read more here.
Keywords: chemotherapy; cell tumours; germ cell; ovarian germ ... See more keywords
miRNA profiles of canine cutaneous mast cell tumours with early nodal metastasis and evaluation as potential biomarkers
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DOI: 10.1038/s41598-020-75877-x
Abstract: Cutaneous mast cell tumours (MCTs) are common skin neoplasms in dogs. MicroRNAs (miRNAs) are post-transcriptional regulators involved in several cellular processes, and they can function as tumour promoters or suppressors. However, the role of miRNAs… read more here.
Keywords: mir; metastasis; mast cell; cell tumours ... See more keywords
Ovarian Sertoli–Leydig cell tumours: How typical is their typical presentation?
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Obstetrics and Gynaecology"
DOI: 10.1080/01443615.2017.1291590
Abstract: Abstract Ovarian Sertoli–Leydig cell tumours (OSLCT) are rare and typically present with androgenic manifestations in women of the 2nd–3rd decade. Out of 228 diagnoses of ovarian sex cord-stromal tumours recorded at an academic institution during… read more here.
Keywords: leydig cell; ovarian sertoli; sertoli leydig; cell tumours ... See more keywords
Prognostic markers in clinical stage I seminoma and nonseminomatous germ cell tumours
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DOI: 10.1097/mou.0000000000000525
Abstract: Purpose of review Testicular germ cell tumour (TGCT) is a common malignancy among young men. There is controversy regarding the best approach for patients with clinical stage I disease due to rates of relapse with… read more here.
Keywords: clinical stage; cell tumours; germ cell;
Epigenetic alterations of testicular germ cell tumours.
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DOI: 10.1097/mou.0000000000000724
Abstract: PURPOSE OF REVIEW Testicular germ cell tumours (TGCTs) exhibit, in contrast to other cancer types, a relatively low mutational burden. However, numerous epigenetic alterations have been shown to impact TGCT. In this review, we summarize… read more here.
Keywords: germ cell; testicular germ; epigenetic alterations; cell tumours ... See more keywords
Decoding germ cell tumours for clinicians
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DOI: 10.1097/mou.0000000000000999
Abstract: Purpose of review Germ-cell tumours of the testis affect predominantly younger males aged between 15 and 40 years, with nearly 74,500 new cases estimated globally in 2020. Their rarity and the complex morphology, mean that, in… read more here.
Keywords: germ cell; decoding germ; cell tumours; management ... See more keywords
The metastatic potential of seminomatous germ cell tumours is associated with a specific microRNA pattern
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DOI: 10.1111/andr.12838
Abstract: Seminomatous germ cell tumours (SGCT) are the most frequent malignancy in young men. Reliable prognostic biomarkers for the prediction of metastasis at diagnosis and the risk of relapse in clinical stage I (CSI) are lacking.… read more here.
Keywords: seminomatous germ; metastatic potential; cell tumours; germ cell ... See more keywords
Multiparametric ultrasound for the diagnosis of Leydig cell tumours in non‐palpable testicular lesions
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DOI: 10.1111/andr.13233
Abstract: The widespread use of ultrasonography has led to an increased number of incidentally detected small non‐palpable lesions, with Leydig cell tumours representing the majority of them. read more here.
Keywords: ultrasound diagnosis; leydig cell; cell tumours; non palpable ... See more keywords