A Combinatorial Library of Lipid Nanoparticles for Cell Type-Specific mRNA Delivery.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202301929
Abstract: Ionizable lipid-based nanoparticles (LNPs) are the most advanced non-viral drug delivery systems for RNA therapeutics and vaccines. However, cell type-specific, extrahepatic mRNA delivery is still a major hurdle, hampering the development of novel therapeutic modalities.… read more here.
Keywords: type specific; delivery; mrna delivery; cell type ... See more keywords
Metabolic Chemical Reporters of Glycans Exhibit Cell‐Type‐Selective Metabolism and Glycoprotein Labeling
Sign Up to like & getrecommendations! Published in 2017 at "ChemBioChem"
DOI: 10.1002/cbic.201700020
Abstract: Since the pioneering work by Reutter and co‐workers that demonstrated structural flexibility in the carbohydrate biosynthesis and glycosylation pathways, many different labs have used unnatural monosaccharide analogues to perform glycan engineering on the surface of… read more here.
Keywords: chemical reporters; cell type; reporters glycans; metabolic chemical ... See more keywords
Cell type specific impact of cannabinoid receptor signaling in somatosensory barrel map formation in mice
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.24733
Abstract: Endocannabinoids and their receptors are highly abundant in the developing cerebral cortex and play major roles in early developmental processes, for example, neuronal proliferation, migration, and axonal guidance as well as postnatal plasticity. To investigate… read more here.
Keywords: type specific; barrel; map; cb1 ... See more keywords
Universal cell type identifier based on number theory
Sign Up to like & getrecommendations! Published in 2018 at "Cytometry Part A"
DOI: 10.1002/cyto.a.23346
Abstract: Cell type classification and handling is a key issue for understanding biological systems. The advent of high multiplexing technologies increased the complexity of the classification process and new tools are needed to support the organization… read more here.
Keywords: type identifier; identifier based; universal cell; cell ... See more keywords
Cell type‐dependent functions of microRNA‐92a
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26765
Abstract: The role of miR‐17/92 family in development and progression of various cancers has been established. The members of this miRNA family have been shown to be over expressed and target various genes within proliferation, metastasis… read more here.
Keywords: family; type dependent; cell; cell type ... See more keywords
Human neural cell type‐specific extracellular vesicle proteome defines disease‐related molecules associated with activated astrocytes in Alzheimer's disease brain
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12183
Abstract: Abstract In neurodegenerative diseases, extracellular vesicles (EVs) transfer pathogenic molecules and are consequently involved in disease progression. We have investigated the proteomic profiles of EVs that were isolated from four different human‐induced pluripotent stem cell‐derived… read more here.
Keywords: disease; type specific; brain; cell type ... See more keywords
Evolution of homology: From archetype towards a holistic concept of cell type
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Morphology"
DOI: 10.1002/jmor.21569
Abstract: The concept of homology lies in the heart of comparative biological science. The distinction between homology as structure and analogy as function has shaped the evolutionary paradigm for a century and formed the axis of… read more here.
Keywords: cell; cell types; evolution; concept ... See more keywords
Profiling Protein-DNA Interactions Cell-Type-Specifically with Targeted DamID.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-2140-0_11
Abstract: Targeted DamID (TaDa) is a means of profiling the binding of any DNA-associated protein cell-type specifically, including transcription factors, RNA polymerase, and chromatin-modifying proteins. The technique is highly sensitive, highly reproducible, requires no mechanical disruption,… read more here.
Keywords: dna; profiling protein; targeted damid; cell type ... See more keywords
Combining Cell Type-Restricted Adenoviral Targeting with Immunostaining and Flow Cytometry to Identify Cells-of-Origin of Lung Cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7568-6_2
Abstract: Lung cancers display considerable intertumoral heterogeneity, leading to the classification of distinct tumor subtypes. Our understanding of the genetic aberrations that underlie tumor subtypes has been greatly enhanced by recent genomic sequencing studies and state-of-the-art… read more here.
Keywords: lung cancer; cells origin; cell type; type restricted ... See more keywords
RETRACTED ARTICLE: Interleukin-33 promotes helper T cell type-2/17 inflammation in children with allergic rhinitis
Sign Up to like & getrecommendations! Published in 2017 at "European Archives of Oto-Rhino-Laryngology"
DOI: 10.1007/s00405-017-4807-1
Abstract: The authors have retracted this article because of significant overlap with a previously published article [1]. All authors agree with this retraction. The online version of this article contains the full text of the retracted… read more here.
Keywords: interleukin promotes; article; retracted article; promotes helper ... See more keywords
UV-B response is modulated by cell-type specific signaling pathway in multicellular green algae Volvox carteri
Sign Up to like & getrecommendations! Published in 2018 at "Plant Growth Regulation"
DOI: 10.1007/s10725-018-0472-7
Abstract: A fundamental question in biology is how multicellular organisms regulate cellular and physiological processes in response to environmental signals in a tissue/cell type-specific manner. Light is one such cue but little is known about its… read more here.
Keywords: specific signaling; type specific; response; cell ... See more keywords