BSA/Chitosan Polyelectrolyte Complex: A Platform for Enhancing the Loading and Cancer Cell-Uptake of Resveratrol
Sign Up to like & getrecommendations! Published in 2018 at "Macromolecular Research"
DOI: 10.1007/s13233-018-6112-2
Abstract: The ultimate goal of cancer therapy is to kill as many cancerous cells while minimizing damage to the normal cells nearby. However, conventional chemotherapy suffers from drug resistance and lack of selectivity and consequently increased… read more here.
Keywords: res bsa; bsa chitosan; cancer; chitosan polyelectrolyte ... See more keywords
In vitro cell uptake evaluation of curcumin-loaded PCL/F68 nanoparticles for potential application in neuronal diseases
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2019.05.042
Abstract: Abstract Curcumin is the major polyphenolic compound of Curcuma longa. It has been found to possess anti-inflammatory and antioxidant activities. The latter property could be exploited as a treatment for neuronal diseases. However, its medical… read more here.
Keywords: application; neuronal diseases; curcumin; cell uptake ... See more keywords
Macrophage-Targeting and Complete Lysosomal Degradation of Self-assembled Two-Dimensional Poly(ε-caprolactone) Platelet Particles.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c06555
Abstract: Understanding cellular uptake and particle trafficking within the cells is essential for targeted drug delivery applications. Existing studies reveal that the geometrical aspects of nanocarriers, for example, shape and size, determine their cell uptake and… read more here.
Keywords: cell; poly caprolactone; two dimensional; cell uptake ... See more keywords
Peptide Brush Polymers and Nanoparticles with Enzyme-Regulated Structure and Charge for Inducing or Evading Macrophage Cell Uptake.
Sign Up to like & getrecommendations! Published in 2017 at "ACS nano"
DOI: 10.1021/acsnano.7b03686
Abstract: Cellular uptake by macrophages and ensuing clearance by the mononuclear phagocyte system stands as a significant biological barrier for nanoparticle therapeutics. While there is a growing body of work investigating the design principles essential for… read more here.
Keywords: macrophage cell; charge; peptide brush; macrophage ... See more keywords
Synthesis and tumour cell uptake studies of gadolinium(III)–phosphonium complexes
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-020-79893-9
Abstract: The synthesis of a new series of Gd(III)-arylphosphonium complexes is described and the solution stability of selected compounds is reported. Their lipophilicity and uptake in human glial (SVG p12) and human glioblastoma multiforme (T98G) cell… read more here.
Keywords: tumour cell; synthesis tumour; uptake studies; studies gadolinium ... See more keywords
Selecting ideal drugs for encapsulation in thermosensitive liposomes and other triggered nanoparticles
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Hyperthermia"
DOI: 10.1080/02656736.2022.2086303
Abstract: Abstract Objective Thermosensitive liposomes (TSL) and other triggered drug delivery systems (DDS) are promising therapeutic strategies for targeted drug delivery. However, successful designs with candidate drugs depend on many variables, including nanoparticle formulation, drug properties,… read more here.
Keywords: cell; thermosensitive liposomes; cell uptake; computer model ... See more keywords
Coronaviruses and Integrin αvβ3: Does Thyroid Hormone Modify the Relationship?
Sign Up to like & getrecommendations! Published in 2020 at "Endocrine Research"
DOI: 10.1080/07435800.2020.1767127
Abstract: ABSTRACT Background Uptake of coronaviruses by target cells involves binding of the virus by cell ectoenzymes. For the etiologic agent of COVID-19 (SARS-CoV-2), a receptor has been identified as angiotensin-converting enzyme-2 (ACE2). Recently it has… read more here.
Keywords: hormone; virus; thyroid hormone; cell uptake ... See more keywords
Gelatin Coating for the Improvement of Stability and Cell Uptake of Hydrophobic Drug-Containing Liposomes
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27031041
Abstract: Purpose: Most therapeutic agents have limitations owing to low selectivity and poor solubility, resulting in post-treatment side effects. Therefore, there is a need to improve solubility and develop new formulations to deliver therapeutic agents specifically… read more here.
Keywords: cell uptake; liposomes gelatin; gelatin coating; stability ... See more keywords
Genetically Engineered Extracellular Vesicles Harboring Transmembrane Scaffolds Exhibit Differences in Their Size, Expression Levels of Specific Surface Markers and Cell-Uptake
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14122564
Abstract: Background: Human cell-secreted extracellular vesicles (EVs) are versatile nanomaterials suitable for disease-targeted drug delivery and therapy. Native EVs, however, usually do not interact specifically with target cells or harbor therapeutic drugs, which limits their potential… read more here.
Keywords: extracellular vesicles; cell uptake; expression; surface markers ... See more keywords