Long non-coding RNAs with peptide-encoding potential identified in esophageal squamous cell carcinoma: KDM4A-AS1-encoded peptide weakens cancer cell viability and migratory capacity.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular oncology"
DOI: 10.1002/1878-0261.13424
Abstract: Currently, the knowledge of long non-coding RNA (lncRNA)-encoded peptides is quite lacking in esophageal squamous cell carcinoma (ESCC). In this study, we simultaneously identified six lncRNA open reading frames (ORFs) with peptide-coding abilities including lysine-specific… read more here.
Keywords: cell; encoded peptide; as1 encoded; kdm4a as1 ... See more keywords
LncRNA EGOT decreases breast cancer cell viability and migration via inactivation of the Hedgehog pathway
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DOI: 10.1002/2211-5463.12833
Abstract: The long noncoding RNA (lncRNA) Eosinophil Granule Ontogeny Transcript (EGOT) has been reported to inhibit the proliferation and migration of glioma cells, and promote the development and progression of gastric cancer through the Hedgehog (Hh)… read more here.
Keywords: cancer; cell viability; viability migration; breast cancer ... See more keywords
Fatostatin ameliorates inflammation without affecting cell viability
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DOI: 10.1002/2211-5463.13364
Abstract: The mature form of sterol regulatory element‐binding protein (SREBP)1 is a transcription factor involved in lipid synthesis, which participates in toll like receptor 4‐triggered inflammatory pathways during the resolution phase of inflammation in macrophages. SREBP1… read more here.
Keywords: affecting cell; fatostatin; cell viability; inflammation ... See more keywords
3D‐Bioprinted Osteoblast‐Laden Nanocomposite Hydrogel Constructs with Induced Microenvironments Promote Cell Viability, Differentiation, and Osteogenesis both In Vitro and In Vivo
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DOI: 10.1002/advs.201700550
Abstract: Abstract An osteoblast‐laden nanocomposite hydrogel construct, based on polyethylene glycol diacrylate (PEGDA)/laponite XLG nanoclay ([Mg5.34Li0.66Si8O20(OH)4]Na0.66, clay)/hyaluronic acid sodium salt (HA) bio‐inks, is developed by a two‐channel 3D bioprinting method. The novel biodegradable bio‐ink A, comprised… read more here.
Keywords: cell viability; laden nanocomposite; viability; nanocomposite hydrogel ... See more keywords
Evaluating cell viability heterogeneity based on information fusion of multiple adhesion strengths
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27749
Abstract: Cell viability evaluation is significantly meaningful for cellular assays. Some cells with weak viability are easily killed in the detection of anticancer drugs, while others with strong viability survive and proliferate, ultimately leading to the… read more here.
Keywords: cell viability; evaluating cell; viability; method ... See more keywords
Cooperation of HIF‐ and NCAM‐mediated mechanisms in cell viability of hippocampal cultures after oxygen–glucose deprivation
Sign Up to like & getrecommendations! Published in 2017 at "Cell Biology International"
DOI: 10.1002/cbin.10825
Abstract: Neurodegenerative diseases of different genesis are the result of cellular damages including those caused by oxygen and glucose deficit. Neuronal survival or death in brain pathologies depends on a variety of interrelated molecular mechanisms. A… read more here.
Keywords: cell viability; viability; glucose deprivation; oxygen glucose ... See more keywords
PGAM4 silencing inhibited glycolysis and chemoresistance to temozolomide in glioma cells
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DOI: 10.1002/cbin.11983
Abstract: Gliomas account for about 80% of malignant brain tumors. The incidence of a new brain tumor is 6.4 per 100,000 persons per year with an overall 5‐year survival rate of 33.4%. Regardless of the great… read more here.
Keywords: pgam4 silencing; glycolysis; glioma; viability proliferation ... See more keywords
Employing QbD strategies to assess the impact of cell viability and density on the primary recovery of monoclonal antibodies
Sign Up to like & getrecommendations! Published in 2022 at "Engineering in Life Sciences"
DOI: 10.1002/elsc.202200056
Abstract: Quality by Design (QbD) is one of the most important tools for the implementation of Process Analytical Technology (PAT) in biopharmaceutical production. For optimal characterization of a monoclonal antibody (mAb) upstream process a stepwise approach… read more here.
Keywords: primary recovery; cell; process; cell viability ... See more keywords
Eriodictyol regulated ferroptosis, mitochondrial dysfunction, and cell viability via Nrf2/HO-1/NQO1 signaling pathway in ovarian cancer cells.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of biochemical and molecular toxicology"
DOI: 10.1002/jbt.23368
Abstract: This study aimed to investigate the antitumor effect and the underlying molecular mechanism of eriodictyol on ovarian cancer cells. CaoV3 and A2780 were exposed to eriodictyol at different concentrations of 0-800 μM. Cell apoptosis and viability… read more here.
Keywords: cell; ovarian cancer; mitochondrial dysfunction; viability ... See more keywords
A rapid and simple spectroscopic method for the determination of yeast cell viability using methylene blue
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DOI: 10.1002/yea.3819
Abstract: Determination of cell viability is important in various microbiological studies. The microscopic method, counting dead cells stained by methylene blue (MB), has often been used for the determination of viability, although it is not efficient… read more here.
Keywords: cell; methylene blue; determination; method ... See more keywords
Endothelin-1-induced hypertrophic alterations and heme oxygenase-1 expression in cardiomyoblasts are counteracted by beta estradiol: in vitro and in vivo studies
Sign Up to like & getrecommendations! Published in 2018 at "Naunyn-Schmiedeberg's Archives of Pharmacology"
DOI: 10.1007/s00210-018-1462-z
Abstract: Endothelin-1 (ET-1), a potent vasoconstrictor normally active in maintaining vascular tone, may mediate significant pathogenic effects, contributing to several serious diseases when aberrantly expressed or regulated. The present study evaluates the capacity of ET-1 to… read more here.
Keywords: cell viability; vitro vivo; heme oxygenase; expression ... See more keywords