Cells adapt to extracellular acidic pH through TM9SF3-mediated PI(4,5)P2 flop
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-63524-w
Abstract: The plasma membrane (PM), a physical barrier separating cells from their environment, responds to fluctuating extracellular environment through receptor-mediated signaling. While these pathways have been extensively studied, the role of PM lipids remains poorly understood.… read more here.
Keywords: cells adapt; extracellular acidic; acidic tm9sf3; pip2 translocation ... See more keywords
Intestinal Epithelial Cells Adapt to Chronic Inflammation through Partial Genetic Reprogramming
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15030973
Abstract: Simple Summary Chronic inflammation, as observed in Crohn’s disease and ulcerative colitis patients, damages the intestinal mucosa. We reasoned that if a subset of intestinal epithelial cells adapt to this inflammatory stress to survive, this… read more here.
Keywords: inflammation; cells adapt; chronic inflammation; partial genetic ... See more keywords