Inhibition of Mitochondrial Metabolism Leads to Selective Eradication of Cells Adapted to Acidic Microenvironment
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DOI: 10.3390/ijms221910790
Abstract: Metabolic transformation of cancer cells leads to the accumulation of lactate and significant acidification in the tumor microenvironment. Both lactate and acidosis have a well-documented impact on cancer progression and negative patient prognosis. Here, we… read more here.
Keywords: acidosis; metabolism; inhibition mitochondrial; cells adapted ... See more keywords