Memory-like NK cells armed with a neoepitope-specific CAR exhibit potent activity against NPM1 mutated acute myeloid leukemia
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DOI: 10.1073/pnas.2122379119
Abstract: Significance Development of effective cellular therapy strategies against acute myeloid leukemia (AML) remains a major therapeutic challenge. Memory-like natural killer (NK) cells armed with a TCR-like chimeric antigen receptor (CAR) targeting a unique neoepitope presented… read more here.
Keywords: myeloid leukemia; memory like; cells armed; car ... See more keywords