Articles with "cells atherosclerosis" as a keyword



Bidirectional effects of IL-10+ regulatory B cells in Ldlr-/- mice.

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Published in 2019 at "Atherosclerosis"

DOI: 10.1016/j.atherosclerosis.2018.11.019

Abstract: BACKGROUND AND AIMS Limiting the pro-inflammatory immune response is critical for the treatment of atherosclerosis. Regulatory B cells (Bregs) can modulate the immune response through interleukin-10 (IL-10). Current data regarding Bregs and atherosclerosis is scarce… read more here.

Keywords: ldlr mice; bidirectional effects; cells atherosclerosis; regulatory cells ... See more keywords

Recent advances on CD4+ T cells in atherosclerosis and its implications for therapy

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Published in 2017 at "European Journal of Pharmacology"

DOI: 10.1016/j.ejphar.2017.04.029

Abstract: Abstract Atherosclerosis is an arterial inflammatory disease and the primary cause of cardiovascular disease. T helper (Th) cells are an important part in atherosclerotic plaque as they can be either disease promoting or protective. A… read more here.

Keywords: advances cd4; cd4 cells; cells atherosclerosis; disease ... See more keywords
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Killer cells in atherosclerosis

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Published in 2017 at "European Journal of Pharmacology"

DOI: 10.1016/j.ejphar.2017.05.009

Abstract: Abstract Cytotoxic lymphocytes (killer cells) play a critical role in host defence mechanisms, protecting against infections and in tumour surveillance. They can also exert detrimental effects in chronic inflammatory disorders and in autoimmune diseases. Tissue… read more here.

Keywords: cells atherosclerosis; pharmacology; killer; killer cells ... See more keywords

Natural killer T cells in atherosclerosis

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Published in 2017 at "Nature Reviews Cardiology"

DOI: 10.1038/nrcardio.2017.2

Abstract: Atherosclerosis is a chronic inflammatory disorder that develops in response to hyperlipidaemia. Cells from both the innate and adaptive immune systems contribute to the development of atherosclerotic lesions. The role of natural killer T (NKT)… read more here.

Keywords: cells atherosclerosis; natural killer; nkt cells; killer cells ... See more keywords

The role of B cells in atherosclerosis

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Published in 2018 at "Nature Reviews Cardiology"

DOI: 10.1038/s41569-018-0106-9

Abstract: The cardiovascular system is subject to hyperlipidaemic, inflammatory, and pro-oxidant stressors. Over time, these factors drive prevalent chronic diseases, of which atherosclerosis is most prominent and accounts for the majority of deaths globally. Antibody-producing B… read more here.

Keywords: cells atherosclerosis; immune responses; role cells; role ... See more keywords

New insights into foam cells in atherosclerosis.

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Published in 2025 at "Cardiovascular research"

DOI: 10.1093/cvr/cvaf202

Abstract: Atherosclerosis, the leading cause of various cardiovascular events, is driven by the expansion of cholesterol-containing foam cells in the arterial intima. Excessive foam cell accumulation triggers apoptosis and necrosis, promoting necrotic core formation and plaque… read more here.

Keywords: new insights; cells atherosclerosis; foam cells; foam cell ... See more keywords
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The many faces of CD8+ T cells in atherosclerosis

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Published in 2018 at "Current Opinion in Lipidology"

DOI: 10.1097/mol.0000000000000541

Abstract: Purpose of review Atherosclerosis and the clinical consequence of cardiovascular disease remain the leading cause of death worldwide. Both an increase in cholesterol levels, as well as immune responses drive the pathogenesis of this disease.… read more here.

Keywords: cells atherosclerosis; cd8 cells; faces cd8; many faces ... See more keywords

Ferroptosis of Macrophages and Endothelial Cells in Atherosclerosis: Molecular Mechanisms and Therapeutic Targets

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Published in 2025 at "Reviews in Cardiovascular Medicine"

DOI: 10.31083/rcm45117

Abstract: Atherosclerosis (AS) is a significant contributor to cardiovascular disease, characterized by abnormal lipid metabolism, cellular apoptosis, oxidative stress, and chronic inflammation. Ferroptosis represents a form of non-apoptotic programmed cell death characterized by the iron-dependent accumulation… read more here.

Keywords: therapeutic targets; ferroptosis; macrophages endothelial; ferroptosis macrophages ... See more keywords