Derivation of Fate-Committed Schwann Cells from Bone Marrow Stromal Cells of Adult Rats.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7649-2_9
Abstract: Our goal is to derive phenotypically stable Schwann cells from bone marrow stromal cells (BMSCs) for use in transplantation studies of central/peripheral nerve injuries. With the adult rat as model, here we describe steps that… read more here.
Keywords: marrow stromal; schwann cells; stromal cells; cells bone ... See more keywords
Prominence of nestin-expressing Schwann cells in bone marrow of patients with myelodysplastic syndromes with severe fibrosis
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Hematology"
DOI: 10.1007/s12185-018-02576-9
Abstract: Nestin-expressing stromal cells (NESCs) and Schwann cells in the bone marrow (BM) play crucial roles as a niche for normal hematopoietic stem cells in mice. It has been reported that both types of cells are… read more here.
Keywords: myelodysplastic syndromes; fibrosis; schwann cells; nestin expressing ... See more keywords
Communication of prostate cancer cells with bone cells via extracellular vesicle RNA; a potential mechanism of metastasis
Sign Up to like & getrecommendations! Published in 2018 at "Oncogene"
DOI: 10.1038/s41388-018-0540-5
Abstract: The role of extracellular vesicles (EVs) as vehicles for cell-to-cell communication between a tumour and its environment is a relatively new concept. The hypothesis that EVs may be critical in co-opting tissues by tumours to… read more here.
Keywords: communication; prostate cancer; pca; cells bone ... See more keywords
Mesenchymal stromal cells in the bone marrow niche consist of multi-populations with distinct transcriptional and epigenetic properties.
Sign Up to like & getrecommendations! Published in 2021 at "Scientific reports"
DOI: 10.1038/s41598-021-94186-5
Abstract: Although multiple studies have investigated the mesenchymal stem and progenitor cells (MSCs) that give rise to mature bone marrow, high heterogeneity in their morphologies and properties causes difficulties in molecular separation of their distinct populations.… read more here.
Keywords: mesenchymal stromal; stromal cells; bone; cells bone ... See more keywords
Immunomagnetic separation of B type acute lymphoblastic leukemia cells from bone marrow with flow cytometry validation and microfluidic chip measurements
Sign Up to like & getrecommendations! Published in 2020 at "Separation Science and Technology"
DOI: 10.1080/01496395.2020.1835983
Abstract: ABSTRACT In order to detect the blast cells from bone marrow of patients, one strategy is to first isolate the cells using immunomagnetic beads. The aim of this study was to report the experimental results… read more here.
Keywords: immunomagnetic separation; separation; cells bone; bone marrow ... See more keywords
Bone Marrow Adipocytes Facilitate Fatty Acid Oxidation Activating AMPK and a Transcriptional Network Supporting Survival of Acute Monocytic Leukemia Cells.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer research"
DOI: 10.1158/0008-5472.can-16-1645
Abstract: Leukemia cells in the bone marrow must meet the biochemical demands of increased cell proliferation and also survive by continually adapting to fluctuations in nutrient and oxygen availability. Thus, targeting metabolic abnormalities in leukemia cells… read more here.
Keywords: leukemia cells; bone; cells bone; marrow adipocytes ... See more keywords
Abstract 5192: Detection of disseminated prostate cancer cells in bone marrow using tyramide signal amplification
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-5192
Abstract: Approximately 28,000 men die of prostate cancer (PCa) each year in the US, and 90-100% of them are due to bone metastasis. It has been demonstrated that PCa cells detach from the primary tumor, “home”… read more here.
Keywords: cancer; cells bone; signal amplification; bone marrow ... See more keywords
Early alterations in stem-like/resident T cells, innate and myeloid cells in the bone marrow in preneoplastic gammopathy.
Sign Up to like & getrecommendations! Published in 2019 at "JCI insight"
DOI: 10.1172/jci.insight.127807
Abstract: Preneoplastic lesions carry many of the antigenic targets found in cancer cells but often exhibit prolonged dormancy. Understanding how the host response to premalignancy is maintained and altered during malignant transformation is needed to prevent… read more here.
Keywords: myeloid cells; bone; stem like; cells bone ... See more keywords
The interaction between osteosarcoma and other cells in the bone microenvironment: From mechanism to clinical applications
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1123065
Abstract: Osteosarcoma is a primary bone tumor with a high mortality rate. The event-free survival rate has not improved significantly in the past 30 years, which brings a heavy burden to patients and society. The high… read more here.
Keywords: clinical applications; osteosarcoma; microenvironment; cells bone ... See more keywords
Osteocytes: New Kids on the Block for Cancer in Bone Therapy
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DOI: 10.3390/cancers15092645
Abstract: Simple Summary This review describes how osteocytes, the most abundant cells in bone, act in cancers that grow in bone. It summarizes how cancer cells reprogram osteocytes to participate in processes associated with tumor growth,… read more here.
Keywords: cancer; bone; cells bone; osteocytes new ... See more keywords
From Stem Cells to Bone-Forming Cells
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22083989
Abstract: Bone formation starts near the end of the embryonic stage of development and continues throughout life during bone modeling and growth, remodeling, and when needed, regeneration. Bone-forming cells, traditionally termed osteoblasts, produce, assemble, and control… read more here.
Keywords: bone forming; forming cells; bone; cells bone ... See more keywords