Recapitulated Crosstalk between Cerebral Metastatic Lung Cancer Cells and Brain Perivascular Tumor Microenvironment in a Microfluidic Co‐Culture Chip
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202201785
Abstract: Non‐small cell lung carcinoma (NSCLC), which affects the brain, is fatal and resistant to anti‐cancer therapies. Despite innate, distinct characteristics of the brain from other organs, the underlying delicate crosstalk between brain metastatic NSCLC (BM‐NSCLC)… read more here.
Keywords: culture; brain; tumor microenvironment; cells brain ... See more keywords
Oligodendroglia-lineage cells in brain plasticity, homeostasis and psychiatric disorders
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Neurobiology"
DOI: 10.1016/j.conb.2017.09.016
Abstract: Adult oligodendrocyte progenitor cells are uniformly distributed in both gray and white matter, displaying robust proliferative and migratory potential during health and disease. Recently, developments in new experimental approaches have brought about several novel insights… read more here.
Keywords: homeostasis; cells brain; brain plasticity; oligodendroglia lineage ... See more keywords
Abstract 6648: Low-intensity pulsed ultrasound enhances the presentation of brain-derived antigens by facilitating the migration of antigen-presenting cells from the brain to the periphery
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-6648
Abstract: Gliomas, the most common primary brain tumors, remain largely incurable despite advancements in surgical and adjuvant therapies. While immunotherapies offer promising avenues, their efficacy has been limited by formidable anatomical barriers, such as the blood-brain… read more here.
Keywords: brain; antigen; migration; cells brain ... See more keywords
T cells in the brain enhance neonatal mortality during peripheral LCMV infection.
Sign Up to like & getrecommendations! Published in 2021 at "PLoS pathogens"
DOI: 10.1371/journal.ppat.1009066
Abstract: In adult mice the severity of disease from viral infections is determined by the balance between the efficiency of the immune response and the magnitude of viral load. Here, the impact of this dynamic is… read more here.
Keywords: cells brain; brain enhance; viral load; mice ... See more keywords
Reconstitution of human microglia and resident T cells in the brain of humanized DRAGA mice
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DOI: 10.3389/fcimb.2024.1367566
Abstract: Humanized mouse models are valuable tools for investigating the human immune system in response to infection and injury. We have previously described the human immune system (HIS)-DRAGA mice (HLA-A2.HLA-DR4.Rag1KO.IL-2RgKO.NOD) generated by infusion of Human Leukocyte… read more here.
Keywords: cells brain; human microglia; brain; draga mice ... See more keywords
Astrocytes: GABAceptive and GABAergic Cells in the Brain
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.892497
Abstract: Astrocytes, the most numerous glial cells in the brain, play an important role in preserving normal neural functions and mediating the pathogenesis of neurological disorders. Recent studies have shown that astrocytes are GABAceptive and GABAergic… read more here.
Keywords: gabaergic cells; brain; gabaceptive gabaergic; astrocytes gabaceptive ... See more keywords