Interstitial cells of Cajal are diminished in critically ill patients: Autopsy cases.
Sign Up to like & getrecommendations! Published in 2019 at "Nutrition"
DOI: 10.1016/j.nut.2019.110591
Abstract: OBJECTIVE Gastrointestinal dysmotility in critically ill patients is important as enteral nutrition is crucial. However, normal gut motility is impaired under conditions of critical illness subsequent to severe insult. Interstitial cells of Cajal (ICC) form… read more here.
Keywords: interstitial cells; ill patients; cajal diminished; critically ill ... See more keywords
Propulsive colonic contractions are mediated by inhibition-driven poststimulus responses that originate in interstitial cells of Cajal.
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2123020119
Abstract: SignificanceThe peristaltic reflex elicits colonic migrating motor complexes (CMMCs) that are thought to be generated by enteric excitatory neurons stimulating smooth muscle cells (SMCs). We found that atropine did not block CMMCs and present a… read more here.
Keywords: colonic contractions; interstitial cells; contractions mediated; propulsive colonic ... See more keywords
Myenteric networks of interstitial cells of Cajal are reduced in horses with inflammatory bowel disease.
Sign Up to like & getrecommendations! Published in 2019 at "Equine veterinary journal"
DOI: 10.1111/evj.13160
Abstract: BACKGROUND Inflammatory bowel disease (IBD) is a well-recognised but poorly understood disease complex in the horse. Clinical signs may vary but often include weight loss, diarrhoea and colic. The effect this disease process may have… read more here.
Keywords: bowel disease; interstitial cells; inflammatory bowel; myenteric networks ... See more keywords
Long-Pulse Gastric Electrical Stimulation Repairs Interstitial Cells of Cajal and Smooth Muscle Cells in the Gastric Antrum of Diabetic Rats
Sign Up to like & getrecommendations! Published in 2018 at "Gastroenterology Research and Practice"
DOI: 10.1155/2018/6309157
Abstract: Background/Aims The damage of interstitial cells of Cajal and smooth muscle cells has far-reaching implications in the pathogenesis of gastroparesis in diabetic patients. Gastric electrical stimulation (GES) is an efficient therapy for gastric motility disorders,… read more here.
Keywords: interstitial cells; muscle; group; muscle cells ... See more keywords
Interstitial Cells of Cajal in Deep Esophageal Leiomyoma
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Surgical Pathology"
DOI: 10.1177/1066896916660197
Abstract: Gastrointestinal stromal tumors (GISTs) are potentially aggressive mesenchymal neoplasms with spindle cell, epithelioid, or mixed morphology. They typically express CD117, DOG1, and CD34 and can be diffusely and strongly positive for h-caldesmon. Leiomyomas are benign… read more here.
Keywords: deep esophageal; cajal deep; interstitial cells; esophageal leiomyoma ... See more keywords
Na+/Ca2 + Exchange and Pacemaker Activity of Interstitial Cells of Cajal
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2020.00230
Abstract: Interstitial cells of Cajal (ICC) are pacemaker cells that generate electrical slow waves in gastrointestinal (GI) smooth muscles. Slow waves organize basic motor patterns, such as peristalsis and segmentation in the GI tract. Slow waves… read more here.
Keywords: interstitial cells; cacc; activation; ca2 ... See more keywords
Interstitial Cells of Cajal—Origin, Distribution and Relationship with Gastrointestinal Tumors
Sign Up to like & getrecommendations! Published in 2022 at "Medicina"
DOI: 10.3390/medicina59010063
Abstract: The interstitial cells of Cajal (ICC) represent a particular network formed by some peculiar cells that were first described by the great neuroanatomist, S. Ramon y Cajal. Nowadays, the ICC have become a fascinating topic… read more here.
Keywords: cells cajal; relationship gastrointestinal; origin distribution; interstitial cells ... See more keywords
Transcriptome and Proteome Profiling of Primary Human Gastric Interstitial Cells of Cajal Predicts Pacemaker Networks
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Neurogastroenterology and Motility"
DOI: 10.5056/jnm22078
Abstract: Background/Aims Interstitial cells of Cajal (ICC) are specialized gastrointestinal (GI) pacemaker cells required for normal GI motility. Dysfunctions in ICC have been reported in patients with GI motility disorders, such as gastroparesis, who exhibit debilitating… read more here.
Keywords: human gastric; cells cajal; transcriptome proteome; icc ... See more keywords