CD8+ Tregs revisited: A heterogeneous population with different phenotypes and properties
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Immunology"
DOI: 10.1002/eji.202048614
Abstract: Regulatory T cells (Tregs) play a key role in the peripheral self‐tolerance and preventing autoimmunity. While classical CD4+ Foxp3+ Tregs are well established, their CD8+ counterparts are still controversial in many aspects including their phenotypic… read more here.
Keywords: cd8; cd8 tregs; cells cd8; revisited heterogeneous ... See more keywords
CD4+T and CD8+T Cells in Uterus Exhibit Both Selective Dysfunction and Residency Signatures
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Immunology Research"
DOI: 10.1155/2024/5582151
Abstract: Unlike T cells in other tissues, uterine T cells must balance strong immune defense against pathogens with tolerance to semiallogeneic fetus. Our previous study fully elucidated the characteristics of γδT cells in nonpregnant uterus and… read more here.
Keywords: cd8 cells; cells cd8; cd4 cells; cd4 ... See more keywords
Killing of Human β-Cells by CD8+ T Cells Triggers Inflammatory Paracrine Signaling and Neighboring β-Cell Dysfunction.
Sign Up to like & getrecommendations! Published in 2025 at "Diabetes"
DOI: 10.2337/db25-0473
Abstract: ARTICLE HIGHLIGHTS In type 1 diabetes, CD8+ T cells destroy pancreatic β-cells. Since most β-cells avoid direct T-cell contact, we asked whether bystander effects drive their dysfunction and loss. We asked whether CD8+ T cells… read more here.
Keywords: killing human; cd8 cells; cells cd8; dysfunction ... See more keywords
An Anti-Tumor Vaccine Against Marek's Disease Virus Induces Differential Activation and Memory Response of γδ T Cells and CD8 T Cells in Chickens
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.645426
Abstract: Marek's disease virus (MDV) is a highly oncogenic alphaherpesvirus that causes deadly T-cell lymphomas and serves as a natural virus-induced tumor model in chickens. The most efficacious vaccine, CVI988/Rispens (CVI988), against MD has been used… read more here.
Keywords: marek disease; disease virus; cells cd8; cells chickens ... See more keywords