Dominant immune cells in pregnancy and pregnancy complications: T helper cells (TH1/TH2, TH17/Treg cells), NK cells, MDSCs, and the immune checkpoints
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DOI: 10.1002/cbin.11955
Abstract: Pregnancy problems including recurrent pregnancy loss, repeated implantation failure and pre‐eclampsia are common problems in the reproductive ages. Different reasons such as genetic, immunological, and environmental agents and also infections could develop these complications. In… read more here.
Keywords: treg cells; immune checkpoints; pregnancy; immune cells ... See more keywords
Basics of Inducible Lymphoid Organs.
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DOI: 10.1007/82_2020_218
Abstract: Tertiary lymphoid organs (TLOs), also known as inducible lymphoid organs, tertiary lymphoid structures, tertiary lymphoid tissues, or ectopic lymphoid organs are accumulations of cells in chronic inflammation that have been observed in most tissues in… read more here.
Keywords: lymphoid organs; inducible lymphoid; microbiology; tertiary lymphoid ... See more keywords
Immunopathogenesis of HBV Infection.
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DOI: 10.1007/978-981-13-9151-4_4
Abstract: More than 95% of adult infected with HBV show acute self-limited infection and eventually eliminate the virus. In contrast, about 90% of people exposed to HBV in early childhood develop chronic infection. The specificity of… read more here.
Keywords: immune; immunopathogenesis hbv; infection; hbv infection ... See more keywords
Suppressive activity of Vδ2+ γδ T cells on αβ T cells is licensed by TCR signaling and correlates with signal strength
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-019-02469-8
Abstract: Despite recent progress in the understanding of γδ T cells’ roles and functions, their interaction with αβ T cells still remains to be elucidated. In this study, we sought to clarify what precisely endows peripheral… read more here.
Keywords: strength; activity; cells licensed; suppressive activity ... See more keywords
CD8+ T Cells and NK Cells: Parallel and Complementary Soldiers of Immunotherapy.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in chemical engineering"
DOI: 10.1016/j.coche.2017.11.006
Abstract: CD8+ T cells and NK cells are both cytotoxic effector cells of the immune system, but the recognition, specificity, sensitivity, and memory mechanisms are drastically different. While many of these topics have been extensively studied… read more here.
Keywords: parallel complementary; cd8 cells; cells parallel; complementary soldiers ... See more keywords
The interplay between innate lymphoid cells and T cells
Sign Up to like & getrecommendations! Published in 2020 at "Mucosal Immunology"
DOI: 10.1038/s41385-020-0320-8
Abstract: ILCs and T cells are closely related functionally but they significantly differ in their ability to circulate, expand, and renew. Cooperation and reciprocal functional regulation suggest that these cell types are more complementary than simply… read more here.
Keywords: interplay innate; innate lymphoid; lymphoid cells; cell ... See more keywords
The deubiquitinase Otub1 controls the activation of CD8 T cells and NK cells by regulating IL-15-mediated priming
Sign Up to like & getrecommendations! Published in 2019 at "Nature immunology"
DOI: 10.1038/s41590-019-0405-2
Abstract: CD8+ T cells and natural killer (NK) cells are central cellular components of immune responses against pathogens and cancer, which rely on interleukin (IL)-15 for homeostasis. Here we show that IL-15 also mediates homeostatic priming… read more here.
Keywords: cd8; deubiquitinase otub1; cd8 cells; activation ... See more keywords
β-Sitosterol inhibits ovalbumin-induced asthma-related inflammation by regulating dendritic cells
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DOI: 10.1080/08923973.2022.2102990
Abstract: Abstract Aim To investigate the effects of β-sitosterol (B-SIT) and the underlying mechanisms of action in an ovalbumin-induced rat model of asthma. Methods The pathological and morphological changes in lung and tracheal tissues were observed… read more here.
Keywords: sit; ovalbumin induced; regulating dendritic; inflammation regulating ... See more keywords
Differential expression of programmed death‐1 according to the histological differentiation of cutaneous squamous cell carcinoma
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DOI: 10.1111/bjd.17850
Abstract: Programmed death-1 (PD-1) is a co-receptor that is expressed on T cells, B cells, natural killer cells, and monocytes. Ligation of PD-1 to its ligand on tumor cells, programmed cell death ligand 1 (PD-L1), induces… read more here.
Keywords: death; differential expression; programmed death; cell ... See more keywords
IL‐23 Activated γδ T Cells Affect Th17 Cells and Regulatory T Cells by Secreting IL‐21 in Children with Primary Nephrotic Syndrome
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DOI: 10.1111/sji.12629
Abstract: This study (1) analysed the percentage of γδ T cells, γδ T cell subsets, Th17 cells and regulatory T cells (Treg cells) and (2) determined the role of IL‐23 in primary nephrotic syndrome (PNS) patients… read more here.
Keywords: percentage cells; treg cells; th17 cells; percentage ... See more keywords
In Vitro Screening and Transfection Concentration Optimization of Cynomolgus Monkey IκBα-siRNA
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DOI: 10.1155/2020/1848540
Abstract: Purpose To seek for a small interfering RNA (siRNA) sequence targeting a cynomolgus monkey inhibitor of nuclear factor kappa B α (IκBα) that can specifically and effectively suppress IκBα gene expression of cynomolgus monkey ciliary… read more here.
Keywords: transfection concentration; cells cells; transfection; cynomolgus monkey ... See more keywords