Chromosome Mis-segregation Generates Cell-Cycle-Arrested Cells with Complex Karyotypes that Are Eliminated by the Immune System.
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DOI: 10.1016/j.devcel.2017.05.022
Abstract: Aneuploidy, a state of karyotype imbalance, is a hallmark of cancer. Changes in chromosome copy number have been proposed to drive disease by modulating the dosage of cancer driver genes and by promoting cancer genome… read more here.
Keywords: complex karyotypes; mis segregation; cell cycle; chromosome mis ... See more keywords