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Published in 2018 at "Immunology"
DOI: 10.1111/imm.12867
Abstract: Type 1 diabetes (T1D) is a T‐cell‐mediated autoimmune disease resulting in islet β‐cell destruction, hypoinsulinaemia and severely altered glucose homeostasis. Although the mechanisms that initiate T1D still remain elusive, a breakdown of immune tolerance between…
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Keywords:
harnessing power;
cells control;
regulatory cells;
control autoimmune ... See more keywords
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Published in 2023 at "Science Advances"
DOI: 10.1126/sciadv.adh1849
Abstract: An overview on the molecular and metabolic mechanisms behind individual cell differences in developmental timing in the segmentation clock and the central nervous system.
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Keywords:
cells control;
time cells;
cell time;
developmental timetables ... See more keywords
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Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.01910
Abstract: Regulatory T-cells (Treg cells), expressing the transcription factor Foxp3, have an essential role in the control of immune homeostasis. In order to control diverse types of immune responses Treg cells must themselves show functional heterogeneity…
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Keywords:
treg cells;
cells control;
follicular regulatory;
regulatory cells ... See more keywords
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Published in 2022 at "eLife"
DOI: 10.7554/elife.80682
Abstract: During renewal of the intestine, cells are continuously generated by proliferation. Proliferation and differentiation must be tightly balanced, as any bias towards proliferation results in uncontrolled exponential growth. Yet, the inherently stochastic nature of cells…
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Keywords:
control daughter;
cell;
proliferation;
mother cells ... See more keywords