In Vitro Identification of Potential Metabolites of Plinabulin (NPI 2358) in Hepatic Preparations Using Liquid Chromatography–Ion Trap Mass Spectrometry
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DOI: 10.1021/acsomega.2c00929
Abstract: Plinabulin (1, NPI2358), a vascular disrupting agent (VDA) molecule, is a synthetic analogue of the natural product phenylahistin (2, NPI 2350), which is isolated from Aspergillus ustus. Evaluation of the in vitro metabolic profile of… read more here.
Keywords: chromatography ion; cells cryopreserved; liquid chromatography; hlms heparg ... See more keywords