The inhibitory receptors on NK cells and CTLs are upregulated in adult and adolescent patients with secondary hemophagocytic lymphohistiocytosis.
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DOI: 10.1016/j.clim.2019.03.006
Abstract: Hemophagocytic lymphohistiocytosis (HLH) includes primary HLH (pHLH) and secondary HLH (sHLH). Mutations that cause abnormal functions in natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) are frequently identified in pHLH. However, why NK cells… read more here.
Keywords: cells ctls; hemophagocytic lymphohistiocytosis; expression; inhibitory receptors ... See more keywords