SGLT-2 Inhibitors and Circulating Progenitor Cells in Diabetes.
Sign Up to like & getrecommendations! Published in 2020 at "Cell metabolism"
DOI: 10.1016/j.cmet.2020.04.002
Abstract: Hess et al. recently hypothesized that shifts in circulating progenitor cell populations may drive cardiovascular protection by SGLT-2 inhibitors in patients with type 2 diabetes. In this Letter, Fadini challenges that interpretation and discusses previous findings… read more here.
Keywords: progenitor cells; circulating progenitor; inhibitors circulating; sglt inhibitors ... See more keywords
Cross talk between exosomes and pancreatic β-cells in diabetes.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of physiology and biochemistry"
DOI: 10.1080/13813455.2020.1760303
Abstract: Exosomes are a class of extracellular vesicles with a diameter of 50-100 nm secreted by various cells. They are generated through complex intracellular production mechanisms before being secreted to the extracellular environment. Due to their inclusion… read more here.
Keywords: cross talk; talk exosomes; exosomes pancreatic; cells diabetes ... See more keywords
Role of Polyamines and Hypusine in β Cells and Diabetes Pathogenesis
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DOI: 10.3390/metabo12040344
Abstract: The polyamines—putrescine, spermidine, and spermine—are polycationic, low molecular weight amines with cellular functions primarily related to mRNA translation and cell proliferation. Polyamines partly exert their effects via the hypusine pathway, wherein the polyamine spermidine provides… read more here.
Keywords: role polyamines; cells diabetes; translation; hypusine cells ... See more keywords