HEK293 cells exposed to microcystin‐LR show reduced protein phosphatase 2A activity and more stable cytoskeletal structure when overexpressing α4 protein
Sign Up to like & getrecommendations! Published in 2017 at "Environmental Toxicology"
DOI: 10.1002/tox.22230
Abstract: Microcystin‐LR (MC‐LR) is one of the most toxic members of microcystins released by freshwater cyanobacterial. The major mechanism of MC‐LR toxicity has been attributed to its inhibition of protein phosphatases 1 (PP1) and 2A (PP2A).… read more here.
Keywords: pp2a; cells exposed; microcystin; hek293 cells ... See more keywords
Anti-apoptotic Effect of Taurine on Schwann Cells Exposed to High Glucose In Vitro.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-8023-5_68
Abstract: It was reported that apoptosis of Schwann cells could increase in the diabetic rats. The studies showed that taurine inhibited apoptosis in a variety of cells. However, there were few reports on studying the protection… read more here.
Keywords: apoptosis; schwann cells; cells exposed; high glucose ... See more keywords
Presence of nano-sized chitosan-layered silicate composites protects against toxicity induced by lead ions.
Sign Up to like & getrecommendations! Published in 2017 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2016.11.084
Abstract: Protecting cells from toxicosis even apoptosis induced by a variety of toxic heavy metals stimulus has drawn more and more attentions. This study was designed to elucidate whether chitosan-organic rectorite (CS-OREC) composites exhibited any protective… read more here.
Keywords: orec composites; presence nano; lead ions; cells exposed ... See more keywords
Transcriptome analysis in normal human liver cells exposed to 2, 3, 3', 4, 4', 5 - Hexachlorobiphenyl (PCB 156).
Sign Up to like & getrecommendations! Published in 2019 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2019.124747
Abstract: BACKGROUNDS Polychlorinated biphenyls are persistent environmental pollutants associated with the onset of non-alcoholic fatty liver disease in humans, but there is limited information on the underlying mechanism. In the present study, we investigated the alterations… read more here.
Keywords: analysis; cells exposed; liver; normal human ... See more keywords
Blockade of Toll-like receptor 4 (TLR4) reduces oxidative stress and restores phospho-ERK1/2 levels in Leydig cells exposed to high glucose.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117365
Abstract: AIMS Hyperglycemia in combination with oxidative stress plays a significant pathophysiological role in diabetic testicular dysfunction, often leading to infertility. Activation of Toll-like receptor 4 (TLR4) has been reported to mediate oxidative stress during diabetes.… read more here.
Keywords: cells exposed; high glucose; tlr4; phospho erk1 ... See more keywords
The compartmentalised nature of the mechanisms governing superoxide formation and scavenging in cells exposed to arsenite.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2019.114766
Abstract: In this study, respiration-proficient (RP) and -deficient (RD) cells were exposed to 2.5 or 10 μM arsenite to generate superoxide (O2-.) respectively in the mitochondrial respiratory chain or via NADPH oxidase activation. These treatments, while causing… read more here.
Keywords: nature mechanisms; compartmentalised nature; cells exposed; formation ... See more keywords
6-OHBDE-47 induces transcriptomic alterations of CYP1A1, XRCC2, HSPA1A, EGR1 genes and trigger apoptosis in HepG2 cells.
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology"
DOI: 10.1016/j.tox.2018.03.007
Abstract: In this study, HepG2 cells were exposed to 6-hydroxy- 2,2',4,4'-tetrabromodiphenyl ether (6-OH-BDE-47) for 3 and 6 days for monitoring cytotoxic effects and alterations in its transcriptomic profile. MTT assay showed that cells exposed to 6-OH-BDE-47 (50 nM)… read more here.
Keywords: ohbde induces; cells exposed; hepg2 cells; apoptosis hepg2 ... See more keywords
Expression patterns of peroxiredoxin genes in bronchial epithelial cells exposed to diesel exhaust particles.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental and molecular pathology"
DOI: 10.1016/j.yexmp.2021.104641
Abstract: Several mechanisms have been suggested to explain the adverse effects of air pollutants on airway cells. One such explanation is the presence of high concentrations of oxidants and pro-oxidants in environmental pollutants. All animal and… read more here.
Keywords: expression patterns; cells exposed; bronchial epithelial; diesel exhaust ... See more keywords
Investigation on the Direct and Bystander Effects in HeLa Cells Exposed to Very Low α-Radiation Using Electrical Impedance Measurement
Sign Up to like & getrecommendations! Published in 2021 at "ACS Omega"
DOI: 10.1021/acsomega.0c05888
Abstract: The impact of radiation-induced bystander effect (RIBE) is still not well understood in radiotherapy. RIBEs are biological effects expressed by nonirradiated cells near or far from the irradiated cells. Most radiological studies on cancer cells… read more here.
Keywords: hela hela; cells exposed; hela; impedance ... See more keywords
A systems biology network analysis of nutri(epi)genomic changes in endothelial cells exposed to epicatechin metabolites
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-33959-x
Abstract: Although vasculo-protective effects of flavan-3-ols are widely accepted today, their impact on endothelial cell functions and molecular mechanisms of action involved is not completely understood. The aim of this study was to characterize the potential… read more here.
Keywords: analysis; cells exposed; epicatechin metabolites; biology ... See more keywords
Investigation of genotoxic effects of paraben in cultured human lymphocytes
Sign Up to like & getrecommendations! Published in 2019 at "Drug and Chemical Toxicology"
DOI: 10.1080/01480545.2017.1414834
Abstract: Abstract Paraben is a phenolic derivative of benzoic acid extensively used as preservatives in food, pharmaceutical, and cosmetic industries due to its antimicrobial characteristics. The objective of this study was to evaluate the in vitro… read more here.
Keywords: 500 250; paraben; cells exposed; genotoxic effects ... See more keywords