Fibrotic Fortresses and Therapeutic Frontiers: Pancreatic Stellate Cells and the Extracellular Matrix in Pancreatic Cancer
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Medicine"
DOI: 10.1002/cam4.70788
Abstract: Pancreatic ductal adenocarcinoma (PDAC) is characterized by a unique tumor microenvironment (TME) that plays pivotal roles in cancer progression, angiogenesis, metastasis, and drug resistance. This complex and dynamic ecosystem comprises cancer cells, stromal cells, and… read more here.
Keywords: cells extracellular; cancer; stellate cells; extracellular matrix ... See more keywords
Stem cells and their extracellular vesicles as natural and bioinspired carriers for the treatment of neurological disorders
Sign Up to like & getrecommendations! Published in 2021 at "Current Opinion in Colloid and Interface Science"
DOI: 10.1016/j.cocis.2021.101460
Abstract: Abstract One of the most explored strategy to cure neurological disorders is the transplantation of stem cells and of their derived products. Different stem cells, as well as their extracellular vesicles (EV), modified or not,… read more here.
Keywords: pre clinical; cells extracellular; stem cells; stem ... See more keywords
Emerging SERS biosensors for the analysis of cells and extracellular vesicles.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale"
DOI: 10.1039/d2nr03005e
Abstract: Cells and their derived extracellular vesicles (EVs) or exosomes contain unique molecular signatures that could be used as biomarkers for the detection of severe diseases such as cancer, as well as monitoring the treatment response.… read more here.
Keywords: analysis cells; sers biosensors; extracellular vesicles; cells extracellular ... See more keywords
Extracellular mixed histones are neurotoxic and modulate select neuroimmune responses of glial cells
Sign Up to like & getrecommendations! Published in 2024 at "PLOS ONE"
DOI: 10.1371/journal.pone.0298748
Abstract: Although histone proteins are widely known for their intranuclear functions where they organize DNA, all five histone types can also be released into the extracellular space from damaged cells. Extracellular histones can interact with pattern… read more here.
Keywords: mixed histones; select neuroimmune; cells extracellular; modulate ... See more keywords
Extracellular Vesicles as an Endocrine Mechanism Connecting Distant Cells
Sign Up to like & getrecommendations! Published in 2022 at "Molecules and Cells"
DOI: 10.14348/molcells.2022.0110
Abstract: The field of extracellular vesicles (EVs) has expanded tremendously over the last decade. The role of cell-to-cell communication in neighboring or distant cells has been increasingly ascribed to EVs generated by various cells. Initially, EVs… read more here.
Keywords: endocrine mechanism; extracellular vesicles; vesicles endocrine; mechanism connecting ... See more keywords
Crosstalk between tongue carcinoma cells, extracellular vesicles, and immune cells in in vitro and in vivo models.
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.17768
Abstract: The crosstalk between immune cells, cancer cells, and extracellular vesicles (EVs) secreted by cancer cells remains poorly understood. We created three-dimensional (3D) cell culture models using human leiomyoma discs and Myogel to study the effects… read more here.
Keywords: extracellular vesicles; vitro vivo; vivo models; cells extracellular ... See more keywords
Light-Sheet Scattering Microscopy to Visualize Long-Term Interactions Between Cells and Extracellular Matrix
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.828634
Abstract: Visualizing interactions between cells and the extracellular matrix (ECM) mesh is important to understand cell behavior and regulatory mechanisms by the extracellular environment. However, long term visualization of three-dimensional (3D) matrix structures remains challenging mainly… read more here.
Keywords: long term; matrix; interactions cells; microscopy ... See more keywords