Real time optical detection of gold in living cells through genetically-encoded probe
Sign Up to like & getrecommendations! Published in 2022 at "RSC Advances"
DOI: 10.1039/d2ra02574d
Abstract: To study the efflux of gold (Au) in living cells, a genetically encoded fluorescence resonance energy transfer (FRET)-based sensor has been developed. The gold-sensing domain GolB from Salmonella typhimurium has been fused to the N-… read more here.
Keywords: gold living; living cells; genetically encoded; real time ... See more keywords
Phase 1 clinical trial of autologous T-cells genetically engineered with a chimeric receptor to target the follicle-stimulating hormone receptor (FSHR) in recurrent ovarian cancer (OVCA).
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2025.43.16_suppl.tps2682
Abstract: TPS2682 Background: FSHR is a tissue specific antigen expressed in > 55% of high-grade epithelial OVCAs with negligible FSHR expression in non-ovarian tissues. OVCA xenografts treated with FSHCER T (FSH-Chimeric Endocrine Receptor + T-Cell (CER… read more here.
Keywords: receptor; ovca; clinical trial; cells genetically ... See more keywords