Immobilization of Escherichia coli cells harboring a nitrilase with improved catalytic properties though polyethylenemine-induced silicification on zeolite.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2021.10.196
Abstract: In the chemical-biological synthesis route of gabapentin, immobilized Escherichia coli cells harboring nitrilase are used to catalyze the biotransformation of intermediate 1-cyanocyclohexaneacetonitile to 1-cyanocyclohexaneacetic acid. Herein, we present a novel cell immobilization method, which is… read more here.
Keywords: escherichia coli; cells harboring; harboring nitrilase; coli cells ... See more keywords
Single-cell TCR sequencing reveals phenotypically diverse clonally expanded cells harboring inducible HIV proviruses during ART
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-17898-8
Abstract: Clonal expansions occur in the persistent HIV reservoir as shown by the duplication of proviral integration sites. However, the source of the proliferation of HIV-infected cells remains unclear. Here, we analyze the TCR repertoire of… read more here.
Keywords: clonal expansions; reservoir; hiv; hiv reservoir ... See more keywords
Abstract 66: Reduction of the Number of Endothelial Cells Harboring Mutations of AVM Causative Genes Lessens Brain AVM Severity
Sign Up to like & getrecommendations! Published in 2019 at "Stroke"
DOI: 10.1161/str.50.suppl_1.66
Abstract: Background and purpose: Mutation of arteriovenous malformation (AVM) causal genes in the endothelial cells (ECs) is essential for AVM formation. However, the relationship of the mutant EC-dose and ... read more here.
Keywords: abstract reduction; reduction number; number endothelial; cells harboring ... See more keywords
Novel Small Molecules Capable of Blocking mtRAS-Signaling Pathway
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.768022
Abstract: RAS mutants are involved in approximately 30% of all human cancers and have been regarded as undruggable targets owing to relatively smooth protein surface and obscure binding pockets. In our previous study, we have demonstrated… read more here.
Keywords: mtras signaling; signaling pathway; cells harboring; cancer cells ... See more keywords
Potential Utility of Natural Killer Cells for Eliminating Cells Harboring Reactivated Latent HIV-1 Following the Removal of CD8+ T Cell-Mediated Pro-Latency Effect(s)
Sign Up to like & getrecommendations! Published in 2021 at "Viruses"
DOI: 10.3390/v13081451
Abstract: An impediment to curing HIV-1 infection is the persistence of latently infected cells in ART-treated people living with HIV (PLWH). A key strategy for curing HIV-1 infection is to activate transcription and translation of latent… read more here.
Keywords: latency; cd8; hiv; pro latency ... See more keywords