PTPN2 Loss Sensitizes Tumor Cells to Immunotherapy.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-rw2017-148
Abstract: Ptpn2 loss increases tumor cell IFNγ signaling to enhance antigen presentation and antitumor immunity. read more here.
Keywords: cells immunotherapy; ptpn2 loss; tumor cells; sensitizes tumor ... See more keywords
NK Cells from Human Pluripotent Stem Cells for Immunotherapy
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-99-115499
Abstract: Natural Killer (NK) cells are a one of innate lymphocytes and show cytotoxicity against tumour cells without prior antigen specific stimulation. . NK cells can demonstrate stronger cytotoxicity than T cells in the absence of… read more here.
Keywords: hpsc derived; cells immunotherapy; medium; derived cells ... See more keywords
Harnessing Unconventional T Cells for Immunotherapy of Tuberculosis
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.02107
Abstract: Even if the incidence of tuberculosis (TB) has been decreasing over the last years, the number of patients with TB is increasing worldwide. The emergence of multidrug-resistant and extensively drug-resistant TB is making control of… read more here.
Keywords: unconventional cells; cells immunotherapy; harnessing unconventional; tuberculosis ... See more keywords
Genetic Modification of T Cells for the Immunotherapy of Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Vaccines"
DOI: 10.3390/vaccines10030457
Abstract: Immunotherapy is a beneficial treatment approach for multiple cancers, however, current therapies are effective only in a small subset of patients. Adoptive cell transfer (ACT) is a facet of immunotherapy where T cells targeting the… read more here.
Keywords: modification cells; tumor; genetic modification; immunotherapy cancer ... See more keywords