Aurantiamide promotes M2 polarization of microglial cells to improve the cognitive ability of mice with Alzheimer's disease
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DOI: 10.1002/ptr.7597
Abstract: This work aimed to investigate the effect of aurantiamide (Aur) in promoting the M2 polarization of microglial cells to improve the cognitive ability of mice with Alzheimer's disease (AD). The M2 polarization of BV2 cells… read more here.
Keywords: microglial cells; ability mice; cells improve; polarization microglial ... See more keywords
Proliferation of endogenous regulatory T cells improve the pathophysiology associated with placental ischaemia of pregnancy
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DOI: 10.1111/aji.12724
Abstract: Preeclampsia (PE) is associated with inflammation and decreased Treg cells and IL‐10. The reduced uterine perfusion pressure (RUPP) rat model of PE exhibits these characteristics, and we hypothesized that induction of endogenous Tregs by a… read more here.
Keywords: improve pathophysiology; cells improve; proliferation endogenous; regulatory cells ... See more keywords
Targeting myeloid cells to improve cancer immune therapy
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DOI: 10.3389/fimmu.2025.1623436
Abstract: Tumor immunosuppression remains a major barrier to effective cancer immunotherapy and is often driven by the immunoregulatory activities of innate immune cells, such as myeloid cells within the tumor microenvironment (TME). Myeloid populations—including tumor-associated macrophages… read more here.
Keywords: myeloid cells; cancer; targeting myeloid; cells improve ... See more keywords