Dendritic cells Trigger IFN‐γ secretion by NK cells independent of IL‐12 and IL‐18
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202149733
Abstract: It is commonly believed that IL‐12 produced by DCs in response to pathogens is the first signal that stimulates the production of IFN‐γ by NK cells. However, IL‐12 production by DCs in response to bacterial… read more here.
Keywords: dcs; ifn production; production; production cells ... See more keywords
Spatial proximity of CD8 T cells to tumor cells as an independent biomarker for response to anti-PD-1 therapy.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.10038
Abstract: 10038Background: Only a subset of advanced melanoma patients respond to anti-PD-1 (aPD1) monotherapy. Upfront identification of (non-)responsiveness would help guide first-line treatment decisions,... read more here.
Keywords: cells independent; cd8 cells; proximity cd8; tumor cells ... See more keywords