Hypoxic adaptation of leukemic cells infiltrating the CNS affords a therapeutic strategy targeting VEGFA.
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DOI: 10.1182/blood-2016-06-721712
Abstract: To the editor: The central nervous system (CNS) is a key site of extramedullary disease in pediatric acute lymphoblastic leukemia (ALL),[1][1] and prior to the development of contemporary risk-adapted treatment strategies, CNS involvement was inevitable… read more here.
Keywords: leukemic cells; cells infiltrating; cns; adaptation leukemic ... See more keywords