Programming CAR-T cells to kill cancer
Sign Up to like & getrecommendations! Published in 2018 at "Nature Biomedical Engineering"
DOI: 10.1038/s41551-018-0235-9
Abstract: T cells engineered to express chimeric antigen receptors (CARs) that are specific for tumour antigens have led to high complete response rates in patients with haematologic malignancies. Despite this early success, major challenges to the… read more here.
Keywords: programming car; kill cancer; car cells; cells kill ... See more keywords
Natural killer cells kill extracellular Pseudomonas aeruginosa using contact-dependent release of granzymes B and H
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010325
Abstract: Pseudomonas aeruginosa is an opportunistic pathogen that often infects individuals with the genetic disease cystic fibrosis, and contributes to airway blockage and loss of lung function. Natural killer (NK) cells are cytotoxic, granular lymphocytes that… read more here.
Keywords: cells kill; cell; pseudomonas aeruginosa; natural killer ... See more keywords