Vma3p protects cells from programmed cell death through the regulation of Hxk2p expression.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.09.041
Abstract: In yeast, the vacuolar proton-pumping ATPase (V-ATPase) acidifies vacuoles to maintain pH of cytoplasm. Yeast cells lacking V-ATPase activity, due to a disruption of any VMA (vacuolar membrane ATPase) gene, remain viable but demonstrate growth… read more here.
Keywords: vma3p; programmed cell; expression; cells lacking ... See more keywords
Cohesin Impedes Heterochromatin Assembly in Fission Yeast Cells Lacking Pds5.
Sign Up to like & getrecommendations! Published in 2019 at "Genetics"
DOI: 10.1534/genetics.119.302256
Abstract: Heterochromatin enriched in histone H3 lysine 9 methylation (H3K9me) and HP1 proteins coats chromosomal domains throughout the eukaryotic genome to regulate gene expression and maintain genome stability. How heterochromatin assembly mechanisms are... The fission yeast… read more here.
Keywords: heterochromatin; cohesin; pds5; heterochromatin assembly ... See more keywords
Overexpression of UBA5 in Cells Mimics the Phenotype of Cells Lacking UBA5
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23137445
Abstract: Ufmylation is a posttranslational modification in which the modifier UFM1 is attached to target proteins. This conjugation requires the concerted work of three enzymes named UBA5, UFC1, and UFL1. Initially, UBA5 activates UFM1 in a… read more here.
Keywords: uba5 ufc1; lacking uba5; overexpression uba5; cells lacking ... See more keywords