Articles with "cells mesenchymal" as a keyword



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Gemcitabine‐induced epithelial‐mesenchymal transition‐like changes sustain chemoresistance of pancreatic cancer cells of mesenchymal‐like phenotype

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Published in 2019 at "Molecular Carcinogenesis"

DOI: 10.1002/mc.23090

Abstract: Growing body of evidence suggests that epithelial‐mesenchymal transition (EMT) is a critical process in tumor progression and chemoresistance in pancreatic cancer (PC). The aim of this study was to analyze the role of EMT‐like changes… read more here.

Keywords: phenotype; chemoresistance; cells mesenchymal; pancreatic cancer ... See more keywords
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Effect of Fibroblast-Like Cells of Mesenchymal Origin of Cytotoxic Activity of Lymphocytes against NK-Sensitive Target Cells

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Published in 2017 at "Bulletin of Experimental Biology and Medicine"

DOI: 10.1007/s10517-017-3658-5

Abstract: We studied immunosuppressive properties of skin fibroblasts and mesenchymal stromal cells against NK cells. In vitro experiments showed that mesenchymal stromal cells isolated from human umbilical cord and human skin fibroblasts can considerably attenuate cytotoxic… read more here.

Keywords: fibroblast like; cells mesenchymal; like cells; activity ... See more keywords
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Comparison of similar cells: Mesenchymal stromal cells and fibroblasts

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Published in 2020 at "Acta Histochemica"

DOI: 10.1016/j.acthis.2020.151634

Abstract: Almost from all organs, both mesenchymal stromal cells and fibroblasts can be isolated. Mesenchymal stromal cells (MSCs) are the most preferred cellular therapeutic agents with the regenerative potential, and fibroblasts are one of the most… read more here.

Keywords: mesenchymal stromal; comparison similar; cells mesenchymal; stromal cells ... See more keywords
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Pathogenic stromal cells as therapeutic targets in joint inflammation

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Published in 2018 at "Nature Reviews Rheumatology"

DOI: 10.1038/s41584-018-0112-7

Abstract: Knowledge of how the joint functions as an integrated unit in health and disease requires an understanding of the stromal cells populating the joint mesenchyme, including fibroblasts, tissue-resident macrophages and endothelial cells. Knowledge of the… read more here.

Keywords: cells mesenchymal; stromal cells; inflammation; mesenchymal origin ... See more keywords
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Niches for Skeletal Stem Cells of Mesenchymal Origin

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Published in 2020 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2020.00592

Abstract: With very few exceptions, all adult tissues in mammals are maintained and can be renewed by stem cells that self-renew and generate the committed progeny required. These functions are regulated by a specific and in… read more here.

Keywords: cells mesenchymal; niches skeletal; stem cell; stem ... See more keywords