ATDC5 cells as a model of cartilage extracellular matrix neosynthesis, maturation and assembly
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Proteomics"
DOI: 10.1016/j.jprot.2020.103718
Abstract: Abstract Fibrillar collagens and proteoglycans (PGs) are quantitatively the major constituents of extracellular matrices (ECM). They carry numerous crucial post-translational modifications (PTMs) that tune the resulting biomechanical properties of the corresponding tissues. The mechanisms determining… read more here.
Keywords: model; atdc5 cells; cells model; cartilage ... See more keywords
HaCaT cells as a model system to study primary cilia in keratinocytes
Sign Up to like & getrecommendations! Published in 2022 at "Experimental Dermatology"
DOI: 10.1111/exd.14626
Abstract: Primary cilium (PC) is a microtubule‐based organelle found on the apical surface of most mammalian cell types, playing a role in development and tissue homeostasis. Ciliopathies are a rapidly growing group of human diseases characterized… read more here.
Keywords: model system; cells model; model; keratinocytes hacat ... See more keywords
Pharmacogenomics with red cells: a model to study protein variants of drug transporter genes
Sign Up to like & getrecommendations! Published in 2020 at "Vox Sanguinis"
DOI: 10.1111/vox.12999
Abstract: The PharmacoScan pharmacogenomics platform screens for variation in genes that affect drug absorption, distribution, metabolism, elimination, immune adverse reactions and targets. Among the 1,191 genes tested on the platform, 12 genes are expressed in the… read more here.
Keywords: cells model; model study; red cells; drug ... See more keywords
A full probabilistic solution of a stochastic red blood cells model using RVT technique
Sign Up to like & getrecommendations! Published in 2021 at "European Physical Journal Plus"
DOI: 10.1140/epjp/s13360-021-01332-z
Abstract: Mathematical modeling is one of the most interesting ways to express the problem that describe the dynamics of the number of red blood cells count in the bloodstream of the human body. This problem has… read more here.
Keywords: cells model; probabilistic solution; blood cells; red blood ... See more keywords
Human Pluripotent Stem Cells to Model Islet Defects in Diabetes
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2021.642152
Abstract: Diabetes mellitus is characterized by elevated levels of blood glucose and is ultimately caused by insufficient insulin production from pancreatic beta cells. Different research models have been utilized to unravel the molecular mechanisms leading to… read more here.
Keywords: human pluripotent; cells model; pluripotent stem; stem ... See more keywords
Quercetin prevents chronic kidney disease on mesangial cells model by regulating inflammation, oxidative stress, and TGF-β1/SMADs pathway
Sign Up to like & getrecommendations! Published in 2022 at "PeerJ"
DOI: 10.7717/peerj.13257
Abstract: Background Chronic kidney disease (CKD) happens due to decreasing kidney function. Inflammation and oxidative stress have been shown to result in the progression of CKD. Quercetin is widely known to have various bioactivities including antioxidant,… read more here.
Keywords: inflammation; stress; kidney; cells model ... See more keywords