Recent advances in mesenchymal stem/stromal cells (MSCs)‐based approaches for osteoarthritis (OA) therapy
Sign Up to like & getrecommendations! Published in 2023 at "Cell Biology International"
DOI: 10.1002/cbin.12008
Abstract: Recently, mesenchymal stem/stromal cells (MSCs) transplantation has been introduced as a promising option to support cartilage structure and improve its function in preclinical models and patients suffering from osteoarthritis (OA). MSCs strongly provoke their preferred… read more here.
Keywords: mscs based; mesenchymal stem; cells mscs; stem stromal ... See more keywords
Mesenchymal stromal cells (MSCs) for neurodegenerative disease: A promising frontier.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of cell biology"
DOI: 10.1016/j.ejcb.2020.151097
Abstract: Neurodegenerative disorders are a variety of diseases including Alzheimer's (AD), Parkinson's (PD), and Huntington's diseases (HD), multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS) along with some other less common diseases generally described by the… read more here.
Keywords: neurodegenerative disease; mesenchymal stromal; mscs neurodegenerative; stromal cells ... See more keywords
Stage-specific differences in secretory profile of mesenchymal stromal cells (MSCs) subjected to early- vs late-stage OA synovial fluid.
Sign Up to like & getrecommendations! Published in 2017 at "Osteoarthritis and cartilage"
DOI: 10.1016/j.joca.2016.11.010
Abstract: OBJECTIVE Although, mesenchymal stromal cells (MSCs) are being clinically investigated for their use in osteoarthritis (OA), it is unclear whether their postulated therapeutic properties are equally effective in the early- and late-stages of OA. In… read more here.
Keywords: late stage; mesenchymal stromal; stromal cells; cells mscs ... See more keywords
Effect of efferocytosis of apoptotic mesenchymal stem cells (MSCs) on C57BL/6 peritoneal macrophages function
Sign Up to like & getrecommendations! Published in 2018 at "Life Sciences"
DOI: 10.1016/j.lfs.2018.09.052
Abstract: ABSTRACT Phagocytic clearance of apoptotic cells (Efferocytosis) could affect the polarization of macrophages and promote M2 anti‐inflammatory and regulatory phenotype and function. Here we tested the hypothesis that efferocytosis of apoptotic Adipose‐Derived Mesenchymal Stem Cells… read more here.
Keywords: efferocytosis apoptotic; efferocytosis; cells mscs; stem cells ... See more keywords
Generation of human pluripotent stem cell lines (iPSCs) from mesenchymal stem cells (MSCs) from three elderly patients with osteoarthritis.
Sign Up to like & getrecommendations! Published in 2020 at "Stem cell research"
DOI: 10.1016/j.scr.2020.101721
Abstract: Mesenchymal stem cells (MSCs) are a unique population of adult stem cells that can differentiate into many cell types. As such, MSCs represent an interesting source of stem cells for use in the clinical treatment… read more here.
Keywords: patients osteoarthritis; cells mscs; elderly patients; stem ... See more keywords
Optimizing conditions for labeling of mesenchymal stromal cells (MSCs) with gold nanoparticles: a prerequisite for in vivo tracking of MSCs
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Nanobiotechnology"
DOI: 10.1186/s12951-017-0258-5
Abstract: BackgroundMesenchymal stromal cells (MSCs) have an inherent migratory capacity towards tumor tissue in vivo. With the future objective to quantify the tumor homing efficacy of MSCs, as first step in this direction we investigated the… read more here.
Keywords: stromal cells; cells mscs; conditions labeling; labeling mesenchymal ... See more keywords
Therapeutic role of mesenchymal stem cells (MSCs) in diabetic kidney disease (DKD).
Sign Up to like & getrecommendations! Published in 2022 at "Endocrine journal"
DOI: 10.1507/endocrj.ej22-0123
Abstract: Findings of preclinical studies and recent phase I/II clinical trials have shown that mesenchymal stem cells (MSCs) play a significant role in the development of diabetic kidney disease (DKD). Thus, MSCs have attracted increasing attention… read more here.
Keywords: kidney; mesenchymal stem; cells mscs; kidney disease ... See more keywords
Senescence induces fundamental changes in the secretome of mesenchymal stromal cells (MSCs): implications for the therapeutic use of MSCs and their derivates
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2023.1148761
Abstract: Mesenchymal stromal cells (MSCs) are a heterogeneous population containing multipotent adult stem cells with a multi-lineage differentiation capacity, which differentiated into mesodermal derivatives. MSCs are employed for therapeutic purposes and several investigations have demonstrated that… read more here.
Keywords: mesenchymal stromal; senescence; cells mscs; mscs ... See more keywords
Cross-Talk Between Mesenchymal Stromal Cells (MSCs) and Endothelial Progenitor Cells (EPCs) in Bone Regeneration
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.674084
Abstract: Bone regeneration is a complex, well-orchestrated process based on the interactions between osteogenesis and angiogenesis, observed in both physiological and pathological situations. However, specific conditions (e.g., bone regeneration in large quantity, immunocompromised regenerative process) require… read more here.
Keywords: mesenchymal stromal; bone regeneration; stromal cells; regeneration ... See more keywords
Mesenchymal Stem Cells and MSCs-Derived Extracellular Vesicles in Infectious Diseases: From Basic Research to Clinical Practice
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineering"
DOI: 10.3390/bioengineering9110662
Abstract: Mesenchymal stem cells (MSCs) are attractive in various fields of regenerative medicine due to their therapeutic potential and complex unique properties. Basic stem cell research and the global COVID-19 pandemic have given impetus to the… read more here.
Keywords: infectious diseases; mesenchymal stem; cells mscs; stem ... See more keywords
Mechanotransduction in Mesenchymal Stem Cells (MSCs) Differentiation: A Review
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23094580
Abstract: Mechanotransduction is the process by which physical force is converted into a biochemical signal that is used in development and physiology; meanwhile, it is intended for the ability of cells to sense and respond to… read more here.
Keywords: mesenchymal stem; cells mscs; mechanotransduction; differentiation ... See more keywords