Granular Mott cells in multiple myeloma
Sign Up to like & getrecommendations! Published in 2021 at "American Journal of Hematology"
DOI: 10.1002/ajh.26216
Abstract: A 64-year-old woman presented to her general practitioner with a several month history of thoracic back pain. Her blood count showed hemoglobin concentration 112 g/L, WBC 5.6 10/L and platelet count 308 10/L. She was… read more here.
Keywords: mott; hematology; multiple myeloma; cells multiple ... See more keywords
Paneth cells and their multiple functions.
Sign Up to like & getrecommendations! Published in 2022 at "Cell biology international"
DOI: 10.1002/cbin.11764
Abstract: The small intestine mucosa is lined by specialized cells that form the crypt-villus axis, which expands its surface. Among the six intestinal epithelial cell types, the Paneth cell is located at the base of the… read more here.
Keywords: multiple functions; cell; cells multiple; paneth cells ... See more keywords
Assessment of commonly used methods to determine myelin-reactivity of T cells in multiple sclerosis.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical immunology"
DOI: 10.1016/j.clim.2021.108817
Abstract: Many studies have analyzed myelin-reactivity of T cells in multiple sclerosis (MS); however, with conflicting results. In this study we compare methods to determine myelin reactivity of T cells and aim to delineate the cause… read more here.
Keywords: methods determine; reactivity cells; multiple sclerosis; reactivity ... See more keywords
Immune genes outside immune cells for multiple sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Neuron"
DOI: 10.1016/j.neuron.2022.03.017
Abstract: In this issue of Neuron, Meijer and Agirre et al. (2022) demonstrate that immune genes exhibit a primed chromatin state in healthy oligodendroglia and are transcriptionally activated in MS through a series of epigenetic activations including… read more here.
Keywords: cells multiple; outside immune; immune genes; multiple sclerosis ... See more keywords
Transcriptional profiling of circulating tumor cells in multiple myeloma: a new model to understand disease dissemination
Sign Up to like & getrecommendations! Published in 2019 at "Leukemia"
DOI: 10.1038/s41375-019-0588-4
Abstract: The reason why a few myeloma cells egress from the bone marrow (BM) into peripheral blood (PB) remains unknown. Here, we investigated molecular hallmarks of circulating tumor cells (CTCs) to identify the events leading to… read more here.
Keywords: transcriptional profiling; tumor cells; circulating tumor; cells multiple ... See more keywords
B cells in multiple sclerosis
Sign Up to like & getrecommendations! Published in 2018 at "Current Opinion in Neurology"
DOI: 10.1097/wco.000000000000563
Abstract: Purpose of review Although it is becoming increasingly clear that B cells play important roles in multiple sclerosis (MS) pathogenesis, it is incompletely understood how they contribute. The purpose of this review is to provide… read more here.
Keywords: sclerosis; neurology; multiple sclerosis; cells multiple ... See more keywords
Abstract 5251: RNA primed SMAR-T cells against multiple driver mutations, all HLA's designed for first line therapy
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-5251
Abstract: Success of immune checkpoint inhibitors (e.g., anti-PD1 antibodies) have revolutionized cancer immunotherapy by demonstrating that a patient’s own T-cells recognize and treat cancer. The efficacy of PD-1 blockade is driven by recruitment of new T-cells… read more here.
Keywords: cells multiple; cancer; therapy; rna primed ... See more keywords
NK cells and multiple myeloma-associated endothelial cells: molecular interactions and influence of IL-27
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.17070
Abstract: Angiogenesis represents a hallmark of tumor progression in Multiple Myeloma (MM), a still incurable malignancy. Here we analyzed the activity of cytokine-stimulated NK cells against tumor-associated endothelial cells isolated from bone marrow aspirates of MM… read more here.
Keywords: myeloma associated; associated endothelial; multiple myeloma; cells multiple ... See more keywords
Fatty Acid Metabolism and T Cells in Multiple Sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.869197
Abstract: Cellular metabolic remodeling is intrinsically linked to the development, activation, differentiation, function, and survival of T cells. T cells transition from a catabolic, naïve state to an anabolic effector state upon T cell activation. Subsequently,… read more here.
Keywords: metabolism; acid metabolism; cells multiple; multiple sclerosis ... See more keywords
Mesenchymal Stem Cells in Multiple Sclerosis: Recent Evidence from Pre-Clinical to Clinical Studies
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21228662
Abstract: Multiple sclerosis (MS) is an autoimmune, demyelinating disease of the central nervous system. Nowadays, available therapies for MS can help to manage MS course and symptoms, but new therapeutic approaches are required. Stem cell therapy… read more here.
Keywords: multiple sclerosis; cells multiple; stem; stem cells ... See more keywords
Scaling Insulin-Producing Cells by Multiple Strategies
Sign Up to like & getrecommendations! Published in 2024 at "Endocrinology and Metabolism"
DOI: 10.3803/enm.2023.1910
Abstract: In the quest to combat insulin-dependent diabetes mellitus (IDDM), allogenic pancreatic islet cell therapy sourced from deceased donors represents a significant therapeutic advance. However, the applicability of this approach is hampered by donor scarcity and… read more here.
Keywords: multiple strategies; cells multiple; insulin producing; insulin ... See more keywords