Allogeneic mesenchymal stromal cells: Novel therapeutic option for mutated FLNA‐associated respiratory failure in the pediatric setting
Sign Up to like & getrecommendations! Published in 2019 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.24497
Abstract: Mesenchymal stromal cell (MSC)‐mediated therapeutic effects have been observed in the treatment of lung diseases. For the first time, this treatment was used as rescue therapy in a pediatric patient with a life‐threatening respiratory syndrome… read more here.
Keywords: mesenchymal stromal; stromal cells; therapeutic option; cells novel ... See more keywords
Interactions Between HDL and CD4+ T Cells: A Novel Understanding of HDL Anti-Inflammatory Properties
Sign Up to like & getrecommendations! Published in 2024 at "Arteriosclerosis, Thrombosis, and Vascular Biology"
DOI: 10.1161/atvbaha.124.320851
Abstract: Several studies in animal models and human cohorts have recently suggested that HDLs (high-density lipoproteins) not only modulate innate immune responses but also adaptative immune responses, particularly CD4+ T cells. CD4+ T cells are central… read more here.
Keywords: cells novel; hdl cd4; cd4 cells; inflammatory ... See more keywords
Smooth Muscle Cells: A Novel Site of P-Selectin Expression with Pathophysiological and Therapeutic Relevance in Pulmonary Hypertension
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Respiratory and Critical Care Medicine"
DOI: 10.1164/rccm.201812-2242ed
Abstract: World Symposium on Pulmonary Hypertension held in Nice in 2018, a change in the definition of PAH was proposed that would decrease the lower limit of mPAP to 20 mm Hg and a pulmonary vascular… read more here.
Keywords: muscle cells; hypertension; smooth muscle; pulmonary hypertension ... See more keywords
Immune Regulatory 1 Cells: A Novel and Potent Subset of Human T Regulatory Cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.790775
Abstract: A subset of T regulatory cells (Tregs), identified by TIRC7 (T cell immune response cDNA 7) expression is designated as Immune Regulatory 1 Cells (IR1 cells). TIRC7 is an immune checkpoint inhibitor, co-localized with the… read more here.
Keywords: cell; regulatory cells; ir1 cells; immune regulatory ... See more keywords
Plasmacytoid Dendritic Cells as a Novel Cell-Based Cancer Immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231911397
Abstract: Plasmacytoid dendritic cells (pDCs) are multifaceted immune cells with a wide range of innate and adaptive immunological functions. They constitute the first line of defence against multiple viral infections and have also been reported to… read more here.
Keywords: novel cell; cells novel; plasmacytoid dendritic; dendritic cells ... See more keywords
Ferroptosis Signaling in Pancreatic β-Cells: Novel Insights & Therapeutic Targeting
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232213679
Abstract: Metabolic stress impairs pancreatic β-cell survival and function in diabetes. Although the pathophysiology of metabolic stress is complex, aberrant tissue damage and β-cell death are brought on by an imbalance in redox equilibrium due to… read more here.
Keywords: cell; pancreatic cells; cells novel; metabolic stress ... See more keywords
Immunomodulatory Effects of LSI312A on Dendritic Cells: A Novel Approach to Modulating Inflammatory Pathways
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Microbiology and Biotechnology"
DOI: 10.4014/jmb.2506.06027
Abstract: Inflammation plays a crucial role in the pathogenesis of various diseases, necessitating the development of effective anti-inflammatory therapeutics. Dendritic cells (DCs), as professional antigen-presenting cells, are key regulators of immune responses. In this study, we… read more here.
Keywords: immunomodulatory effects; inflammatory pathways; effects lsi312a; dendritic cells ... See more keywords