Senkyunolide H protects PC12 cells from OGD/R-induced injury via cAMP-PI3K/AKT signaling pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2021.114659
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Senkyunolide H (SNH) is a bioactive phthalide isolated from Ligusticum chuanxiong Hort rhizome and was reported to have multiple pharmacological effects. AIM OF THE STUDY The study was performed to verify the potency… read more here.
Keywords: camp; pc12 cells; ogd induced; cells ogd ... See more keywords
Chrysin, which targets PLAU, protects PC12 cells from OGD/R-stimulated damage through repressing the NF-κB signaling pathway
Sign Up to like & getrecommendations! Published in 2022 at "Regenerative Therapy"
DOI: 10.1016/j.reth.2021.11.002
Abstract: Cerebral ischemia reperfusion injury (CIRI) is a great challenge for the patients with brain ischemia, but its pathophysiological mechanism has not been clearly explored. This study aims to decipher the effect of chrysin and plasminogen… read more here.
Keywords: pc12 cells; stimulated damage; ogd stimulated; chrysin ... See more keywords