Generation of germ cells from pluripotent stem cells in mammals
Sign Up to like & getrecommendations! Published in 2018 at "Reproductive Medicine and Biology"
DOI: 10.1002/rmb2.12077
Abstract: The germ cell lineage transmits genetic and epigenetic information to the next generation. Primordial germ cells (PGCs), the early embryonic precursors of sperm or eggs, have been studied extensively. Recently, in vitro models of PGC… read more here.
Keywords: cells pluripotent; generation germ; germ cells; generation ... See more keywords
Asymmetricity Between Sister Cells of Pluripotent Stem Cells at the Onset of Differentiation.
Sign Up to like & getrecommendations! Published in 2018 at "Stem Cells and Development"
DOI: 10.1089/scd.2017.0113
Abstract: Various somatic stem cells divide asymmetrically; however, it is not known whether embryonic stem cells (ESCs) divide symmetrically or asymmetrically, not only while maintaining an undifferentiated... read more here.
Keywords: cells pluripotent; asymmetricity sister; pluripotent stem; stem ... See more keywords
Functional primordial germ cell–like cells from pluripotent stem cells in rats
Sign Up to like & getrecommendations! Published in 2022 at "Science"
DOI: 10.1126/science.abl4412
Abstract: The in vitro generation of germ cells from pluripotent stem cells (PSCs) can have a substantial effect on future reproductive medicine and animal breeding. A decade ago, in vitro gametogenesis was established in the mouse.… read more here.
Keywords: germ; cells pluripotent; pluripotent stem; germ cells ... See more keywords