Toll-like receptor 2 induced cytotoxic T-lymphocyte-associated protein 4 regulates Aspergillus-induced regulatory T-cells with pro-inflammatory characteristics
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DOI: 10.1038/s41598-017-11738-4
Abstract: Patients with cystic fibrosis, chronic obstructive pulmonary disease, severe asthma, pre-existing pulmonary lesions, and severely immunocompromised patients are susceptible to develop infections with the opportunistic pathogenic fungus Aspergillus fumigatus, called aspergillosis. Infections in these patients… read more here.
Keywords: phenotype; th17 like; immunopathology; cells pro ... See more keywords
Siponimod Modulates the Reaction of Microglial Cells to Pro-Inflammatory Stimulation
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DOI: 10.3390/ijms232113278
Abstract: Siponimod (Mayzent®), a sphingosine 1-phosphate receptor (S1PR) modulator which prevents lymphocyte egress from lymphoid tissues, is approved for the treatment of relapsing-remitting and active secondary progressive multiple sclerosis. It can cross the blood–brain barrier (BBB)… read more here.
Keywords: modulates reaction; microglial cells; reaction microglial; siponimod modulates ... See more keywords