circ_0089153 exacerbates breast cancer cells proliferation and metastasis via sponging miR‐2467‐3p/E2F6
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23498
Abstract: The role of circ_0089153 in breast cancer (BCa) malignancy development was explored. circ_0089153 expression in BCa was analyzed by Gene Expression Omnibus database. Clinical tissues were obtained from 90 BCa patients. Cell counting kit‐8 assay,… read more here.
Keywords: metastasis; cells proliferation; mir 2467; bca ... See more keywords
Design, synthesis and anti leukemia cells proliferation activities of pyrimidylaminoquinoline derivatives as DOT1L inhibitors.
Sign Up to like & getrecommendations! Published in 2018 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2018.07.022
Abstract: A series of novel pyrimidylaminoquinoline derivatives 8(a-i) and 9(a-i) containing amino side chain, and the bisaminoquinoline analogs 3(b-e) have been designed and synthesized by structural modifications on a lead DOT1L inhibitor, 3a. All the compounds… read more here.
Keywords: leukemia cells; proliferation activities; pyrimidylaminoquinoline derivatives; cells proliferation ... See more keywords
Nicotine promotes WRL68 cells proliferation due to the mutant p53 gain-of-function by activating CDK6-p53-RS-PIN1-STAT1 signaling pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.0c00119
Abstract: The liver is an important organ with many tasks, such as dealing with drugs, alcohol and other toxins to remove them from the body. Nicotine is the more abundant component in cigarette smoking, which is… read more here.
Keywords: wrl68 cells; stat1; cells proliferation; mutant p53 ... See more keywords
Acetylcholine regulates the development of experimental autoimmune encephalomyelitis via the CD4+ cells proliferation and differentiation
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Neuroscience"
DOI: 10.1080/00207454.2019.1706504
Abstract: Abstract Purpose of the study: Multiple sclerosis is a CD4+ T cell mediated autoimmune disease characterized by inflammatory demyelination in the central nervous system. Acetylcholine (ACh) has been reported to be released by T lymphocytes… read more here.
Keywords: cd4 cells; cells proliferation; autoimmune encephalomyelitis; cd4 ... See more keywords
Nicotine Promotes Human Papillomavirus (HPV)-Immortalized Cervical Epithelial Cells (H8) Proliferation by Activating RPS27a-Mdm2-P53 Pathway In Vitro
Sign Up to like & getrecommendations! Published in 2019 at "Toxicological Sciences"
DOI: 10.1093/toxsci/kfy246
Abstract: HPV infection is the main risk factor for cervical cancer, but it is still an insufficient event for the development of this cancer. It has demonstrated that nicotine plays an important role in cervical carcinogenesis.… read more here.
Keywords: mdm2; proliferation; cells proliferation; nicotine promotes ... See more keywords
Silencing CAPN2 Expression Inhibited Castration-Resistant Prostate Cancer Cells Proliferation and Invasion via AKT/mTOR Signal Pathway
Sign Up to like & getrecommendations! Published in 2017 at "BioMed Research International"
DOI: 10.1155/2017/2593674
Abstract: The mRNA expression of CAPN2 was upregulated in CRPC cells (DU145 and PC3) than that in non-CRPC cells. Silencing CAPN2 expression could inhibit DU145 and PC3 cells proliferation by cell cycle arrest at G1 phase.… read more here.
Keywords: capn2 expression; crpc cells; cells proliferation; silencing capn2 ... See more keywords
Circ-ITCH correlates with less advanced tumor features as well as prolonged survival, and it inhibits cells proliferation but promotes apoptosis in non-small cell lung cancer
Sign Up to like & getrecommendations! Published in 2019 at "Translational cancer research"
DOI: 10.21037/30712
Abstract: Background: This study was to investigate the correlation of circ-ITCH expression with tumor features, disease free survival (DFS) and overall survival (OS) in non-small cell lung cancer (NSCLC) patients, and the effect of its dysregulation… read more here.
Keywords: itch; circ itch; cells proliferation; cell ... See more keywords
Circ-ITCH correlates with less advanced tumor features as well as prolonged survival, and it inhibits cells proliferation but promotes apoptosis in non-small cell lung cancer
Sign Up to like & getrecommendations! Published in 2019 at "Translational Cancer Research"
DOI: 10.21037/tcr.2019.08.01
Abstract: Background This study was to investigate the correlation of circ-ITCH expression with tumor features, disease free survival (DFS) and overall survival (OS) in non-small cell lung cancer (NSCLC) patients, and the effect of its dysregulation… read more here.
Keywords: tumor; cells proliferation; cell; circ itch ... See more keywords
Atorvastatin inhibits pancreatic cancer cells proliferation and invasion likely by suppressing neurotrophin receptor signaling
Sign Up to like & getrecommendations! Published in 2020 at "Translational cancer research"
DOI: 10.21037/tcr.2020.01.27
Abstract: Pancreatic cancer (PC) is a devastating disease with an extremely poor median survival of less than 6 months due to its aggressive nature. Each year, approximately 40,000 individuals are diagnosed with this lethal malignancy worldwide.… read more here.
Keywords: atorvastatin inhibits; inhibits pancreatic; pancreatic cancer; cells proliferation ... See more keywords
MiR-9-5p Inhibits Glioblastoma Cells Proliferation Through Directly Targeting FOXP2 (Forkhead Box P2)
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2019.01176
Abstract: Glioblastoma (GBM) is the most malignant tumor in the central nervous system and the treatment is still unsatisfactory because the mechanism of the disease remains unclear. The abnormal expression of miRNAs and its target proteins… read more here.
Keywords: forkhead box; cells proliferation; expression; proliferation ... See more keywords
N6-Methyladenosine Modification of LncRNA DUXAP9 Promotes Renal Cancer Cells Proliferation and Motility by Activating the PI3K/AKT Signaling Pathway
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.641833
Abstract: Most localized human renal clear cell carcinoma (ccRCC)-related deaths result from cancer recurrence and metastasis. However, the precise molecular mechanisms largely remain unknown. In recent years, an increasing number of long noncoding RNAs (lncRNAs) have… read more here.
Keywords: duxap9; proliferation motility; cells proliferation; cancer cells ... See more keywords