Design, synthesis and biological evaluation of vincamine derivatives as potential pancreatic β-cells protective agents for the treatment of type 2 diabetes mellitus.
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DOI: 10.1016/j.ejmech.2019.111976
Abstract: A series of vincamine derivatives were designed, synthesized and evaluated as pancreatic β-cells protective agents for type 2 diabetes mellitus. Most of the compounds displayed potent pancreatic β-cells protective activities and five derivatives were found… read more here.
Keywords: protective agents; type diabetes; diabetes mellitus; pancreatic cells ... See more keywords