Development of a 3D psoriatic skin model optimized for infiltration of IL-17A producing T cells: focus on the crosstalk between T cells and psoriatic keratinocytes.
Sign Up to like & getrecommendations! Published in 2021 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2021.09.018
Abstract: Psoriasis is a chronic inflammatory skin disease involving several cell types, including T cells, via the IL-23/IL-17 axis. IL-17A acts on the surrounding epithelial cells thus resulting in an inflammatory feedback loop. The development of… read more here.
Keywords: psoriatic skin; model; cells psoriatic; skin model ... See more keywords
Enrichment of polyfunctional T cells in PsA synovial tissue. Response to: 'Polyfunctional TEM cells in psoriatic arthritis synovium skewed towards Th17 cells' by Raychaudhuri et al.
Sign Up to like & getrecommendations! Published in 2020 at "Annals of the rheumatic diseases"
DOI: 10.1136/annrheumdis-2019-216814
Abstract: We read with interest the research letter by Raychaudhuri et al , which examines the frequencies of cytokine producing CD4+ memory T cells in psoriatic arthritis (PsA) and rheumatoid arthritis (RA) synovial fluid mononuclear cells… read more here.
Keywords: psoriatic arthritis; synovial tissue; th17 cells; cells psoriatic ... See more keywords