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Abstract 3102: Venetoclax resistance associates with high-level expression of ROR1 and cancer stemness in chronic lymphocytic leukemia

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Published in 2021 at "Tumor Biology"

DOI: 10.1158/1538-7445.am2021-3102

Abstract: The BH3-mimetic venetoclax is highly cytotoxic for chronic lymphocytic leukemia (CLL) cells. Nonetheless, some patients (pts) fail to clear minimal residual disease (MRD) and develop progressive disease (PD) on venetoclax-based therapy (V-Rx). Acquisition of de… read more here.

Keywords: venetoclax; cancer; resistance; cll cells ... See more keywords