Human T cells recognize HLA-DP–bound peptides in two orientations
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2214331119
Abstract: Significance Human leukocyte antigens (HLAs) present peptides to T cells, thereby allowing them to recognize pathogen-infected and cancer cells. Conventionally, it was thought that peptides bind to HLA molecules in a conserved N- to C-terminal… read more here.
Keywords: bound peptides; cells recognize; hla; human cells ... See more keywords
How cells recognize and remove the perforated lysosome.
Sign Up to like & getrecommendations! Published in 2022 at "Autophagy"
DOI: 10.1080/15548627.2022.2138686
Abstract: Macroautophagy (hereafter autophagy) is a highly conserved intracellular degradation system to maintain cellular homeostasis by degrading cellular components such as misfolded proteins, nonfunctional organelles, pathogens, and cytosol. Conversely, selective autophagy targets and degrades specific cargo,… read more here.
Keywords: remove perforated; cells recognize; recognize remove; perforated lysosome ... See more keywords