Checkpoint Receptor TIGIT Expressed on Tim-1+ B Cells Regulates Tissue Inflammation.
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DOI: 10.1016/j.celrep.2020.107892
Abstract: Tim-1, a phosphatidylserine receptor expressed on B cells, induces interleukin 10 (IL-10) production by sensing apoptotic cells. Here we show that mice with B cell-specific Tim-1 deletion develop tissue inflammation in multiple organs including spontaneous… read more here.
Keywords: tim cells; cells regulates; inflammation; receptor ... See more keywords
The metabolism of cells regulates their sensitivity to NK cells depending on p53 status
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-022-07281-6
Abstract: Leukemic cells proliferate faster than non-transformed counterparts. This requires them to change their metabolism to adapt to their high growth. This change can stress cells and facilitate recognition by immune cells such as cytotoxic lymphocytes,… read more here.
Keywords: regulates sensitivity; metabolism cells; p53; cells regulates ... See more keywords