IL-1R8 is a checkpoint in NK cells regulating anti-tumor and anti-viral activity
Sign Up to like & getrecommendations! Published in 2017 at "Nature"
DOI: 10.1038/nature24293
Abstract: Interleukin-1 receptor 8 (IL-1R8, also known as single immunoglobulin IL-1R-related receptor, SIGIRR, or TIR8) is a member of the IL-1 receptor (ILR) family with distinct structural and functional characteristics, acting as a negative regulator of… read more here.
Keywords: cells regulating; 1r8 checkpoint; regulating anti; checkpoint ... See more keywords
FOXM1‐mediated NUF2 expression confers temozolomide resistance to human glioma cells by regulating autophagy via the PI3K/AKT/mTOR signaling pathway
Sign Up to like & getrecommendations! Published in 2022 at "Neuropathology"
DOI: 10.1111/neup.12824
Abstract: Glioma is the most common malignant tumor in the central nervous system and has a high mortality rate. Temozolomide (TMZ) is a widely used chemotherapeutic drug for glioma. NDC80 kinetochore complex (NUF2) is suggested to… read more here.
Keywords: cells regulating; tmz resistant; glioma cells; human glioma ... See more keywords
The regulating role of miR-494 on HCCR1 in cervical cancer cells.
Sign Up to like & getrecommendations! Published in 2022 at "Cellular and molecular biology"
DOI: 10.14715/cmb/2021.67.5.18
Abstract: This study focused on miR-494 inhibiting the proliferation, migration and invasion of cervical cancer cells by regulating HCCR1. During the study, 30 pairs of primary cervical cancer tissues and adjacent tissues diagnosed by pathology were… read more here.
Keywords: cervical cancer; cancer; cells regulating; regulating role ... See more keywords
β-Catenin Controls the Electrophysiologic Properties of Skeletal Muscle Cells by Regulating the α2 Isoform of Na+/K+-ATPase
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2019.00831
Abstract: β-Catenin is a key component of the canonical Wnt signaling pathway. It has been shown to have an important role in formation of the neuromuscular junction. Our previous studies showed that in the absence of… read more here.
Keywords: skeletal muscle; cells regulating; catenin; electrophysiologic properties ... See more keywords