Treg cells require Izumo1R to regulate γδT cell-driven inflammation in the skin.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2221255120
Abstract: Izumo1R is a pseudo-folate receptor with an essential role in mediating tight oocyte/spermatozoa contacts during fertilization. Intriguingly, it is also expressed in CD4+ T lymphocytes, in particular Treg cells under the control of Foxp3. To… read more here.
Keywords: treg; inflammation; skin; cell ... See more keywords
Sertoli cells require TDP-43 to support spermatogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioac165
Abstract: Abstract TAR DNA binding protein of 43 kD (TDP-43) is an evolutionarily conserved, ubiquitously expressed transcription factor and RNA-binding protein with major human health relevance. TDP-43 is present in Sertoli and germ cells of the… read more here.
Keywords: spermatogenesis; sertoli; germ; cells require ... See more keywords
Unraveling a mystery: Why human cells require cholesterol
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.ade5927
Abstract: Understanding how cholesterol binds to mammalian cells offers critical insights into the waxy substance’s role in protein modulation and cell function. read more here.
Keywords: mystery human; human cells; cells require; unraveling mystery ... See more keywords