Articles with "cells ruxolitinib" as a keyword



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Epigenetic modifications in chronic myeloid leukemia cells through ruxolitinib treatment

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Published in 2019 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.27744

Abstract: Chronic myeloid leukemia is a clonal malignancy of hematopoietic stem cell that is characterized by the occurrence of t(9;22)(q34;q11.2) translocation, named Philadelphia chromosome. Ruxolitinib is a powerful Janus tyrosine kinase 1 and 2 inhibitor that… read more here.

Keywords: epigenetic modifications; ruxolitinib treatment; cells ruxolitinib; myeloid leukemia ... See more keywords